한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)
- 제20권1호통권32호
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- Pages.51-65
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- 2007
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
괴화(槐花) 추출물의 투여(投與)가 Streptozotocin으로 유발된 당뇨쥐에 미치는 영향
Effects of Sophorae Flos on Steptozotocin-induced Diabetic Mellitus in Rats
- 발행 : 2007.04.25
초록
Objective : The present study was carried out to investigate the preventive effect of Sophorae Flos on streptozotocin - induced Diabetes mellitus. Method : Sophorae Flos was given to rats with oral administration. The experimental animals were divided into 3groups : normal group of rats, control group of Streptozotocin-induced diabetic rats, sample group with Sophorae Flos . The effect of Sophorae Flos on Streptozotocin-induced diabetes was observed by measuring the survival rate of rats, weight of rats, FER, blood glucose, each organ weight of rat, total cholesterol, HDL, GOT, GPT & creatinine. Result : Streptozotocin caused hyperglycemia and hypoinsulinemia by a selectively destroying pancreatic