Applied Biological Chemistry

  • 제50권3호
  • /
  • Pages.210-216
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  • 2007
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  • 2468-0834(pISSN)
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  • 2468-0842(eISSN)
한국응용생명화학회 (The Korean Society for Applied Biological Chemistry)
권호 표지

방사선 조사 및 녹차 폴리페놀을 첨가한 화장품의 항균효과

Anti-microbial Effect of Irradiated Green Tea Polyphenol Addition into Cosmetic Composition

  • 박태순 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 현석준 (대구한의대학교 화장품약리학과) ;
  • 박근혜 (대구한의대학교 화장품약리학과) ;
  • 조영제 (상주대학교 식품공학과) ;
  • 김세기 ((주)이지함 화장품) ;
  • 안봉전 (대구한의대학교 화장품약리학과)
  • Park, Tae-Soon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Hyun, Sok-Jun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Gun-Hye (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Cho, Young-Je (Department of Food Engineering, Sangju National University) ;
  • Kim, Se-Gie (LeeJiHam Cosmetics Ltd.) ;
  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University)
  • 발행 : 2007.09.30
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초록

방사선 조사한 녹차 폴리페놀을 스킨과 에센스에 첨가하여 방부제를 첨가하지 않았을 때의 항균효과 및 방부효과를 검증하고 무방부제 화장품으로서의 가능성을 검토하였다. 항균력 측정 결과, C. albicans를 제외한 모든 균주에서 항균효과가 나타났으며, 피부상재균인 S. aureus에서 항균효과가 높게 나타났다. MIC 측정 결과, E. coli와 C. albicans의 경우 2,500 ppm에서, S. aureus의 경우 1,000 ppm에서 저해농도를 나타내었으며, MBC 측정 결과, C. albicans를 제외한 모든 균주에서 측정이 가능하였으며, E. coli의 경우 10,000 ppm, S. aureus의 경우 5,000 ppm에서 모든 균이 사멸하였다. 시간에 따른 생균수 측정 결과, 시간이 지남에 따라 균의 증식을 억제하여 항균력이 뛰어남을 알 수 있었다. 이와 같은 결과로 미루어 보아 녹차폴리페놀은 스킨과 에센스에 첨가 시 항균효과가 우수하여 화장품 첨가제로 이용이 가능할 것으로 사료된다.

Cosmetic products including skin and essence were manufactured to analyze the effect of green tea polyphenols addition. In addition, irradiation was applied to remove an undesirable color of green tea polyphenol(GTP), which may cause a problem in the marketing, of a final product; moreover, comparative studies were conducted with the cosmetic products on whether or not antiseptics were treated to verify its use for the development of non-antiseptic cosmetic products. Growth inhibition zones were shown in the microbial study except for Candida albicans. The minimum inhibitory concentration(MIC) of E. coli and C. albicans was 2,500 ppm but that of S. aureus was 1,000 ppm. The numbers of E. coli and S. aureus were reduced to undetected levels when 10,000 and 5,000 ppm of polyphenol were added, respectively. Results indicate that the addition of irradiated green tea polyphenol provides a good method to manufacture functional cosmetics including skin and essence with various biological activities such as antimicrobial activity without antiseptics.

키워드

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