Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Nucleoside Constituents of the Egyptian Tunicate Eudistoma laysani

  • Abou-Hussein, Dina R. (Department of Pharmacognosy, Faculty of Pharmacy, Cairo University) ;
  • Badr, Jihan M. (Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University) ;
  • Youssef, Diaa T.A. (Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University)
  • Published : 2007.09.30
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Abstract

Chemical investigation of the crude extract of the Egyptian marine tunicate Eudistoma laysani led to the isolation of a new nucleoside; 3-deazainosine and four known ones; inosine, 2'-deoxyuridine, adenosine and 2'-deoxyadenosine. Structural elucidation of the isolated compounds was based on intensive studies of their spectral data including 1D ($^{1}H$ and $^{13}C$) and 2D ($^{1}H-^{1}H$ COSY, HMQC, HMBC) NMR together with mass spectra. The antioxidant effects of the isolated compounds were determined using DPPH, where they exhibited significant activities.

Keywords

References

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