Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
권호 표지
DOI QR코드

DOI QR Code

Short Communication Antinociceptive activity of Avicennia officinalis

  • Shahid, IZ (Pharmacy Discipline, Khulna University) ;
  • Karmakar, D (Pharmacy Discipline, Khulna University) ;
  • Sadhu, SK (Pharmacy Discipline, Khulna University) ;
  • Ahmed, F (Pharmacy Discipline, Khulna University)
  • Published : 2007.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

The crude ethanol extract of leaves of Avicennia officinalis Linn. (Family: Avicenniaceae) was screened for its antinociceptive activity. The extract produced significant writhing inhibition in acetic acid-induced writhing in mice at the oral dose of 250 and 500 mg/kg body weight (P < 0.001) comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight. The result tends to suggest the antinociceptive activity of the extract.

Keywords

References

  1. Ahmed F, Selim MST, Das AK, Choudhuri MSK (2004) Anti-inflammatory and antinociceptive activities of Lippia nodiflora Linn. Pharmazi. 59,329-330
  2. Balasooriya SJ, Sotheeswaran S, Balasubramanium S. (1982) Economically useful plants of Sri Lanka, Part IV. J. Nat. Sci. Counc. 10, 213-219
  3. Basak UC. Das AB, Das P. (1996) Chlorophyll, carotenoids, proteins, and secondary metabolites in leaves of 14 species of mangroves. Bull. Mar. Sci. 58, 654-659
  4. Derardt R, Jougney S, Delevalcee F, Falhout M. (1980) Release of prostaglandins E and F in an algogenic reaction and its inhibition. Eur. J. Pharmacol. 51, 1724
  5. Evans WC (1989) Trease and Evan's Textbook of Pharmacognosy. 13th edition, p. 546, Cambridge University Press, London
  6. Ghani A. (1998) Medicinal Plants of Bangladesh. 1st edition, The Asiatic Society of Bangladesh, Dhaka, Bangladesh
  7. Ghosh A, Misra S, Dutta AK, Choudhury A. (1985) Pentacyc1ic triterpenoids and sterols from seven species of mangrove. Phytochemistry 24, 1725-1727
  8. Kirtikar KR, Basu BD. (1987) Indian Medicinal Plants. 2nd ed. International Book Distributors, p. 1952-1953, India
  9. Sharma M, Garg HS. (1996) Iridoid glycosides from Avicennia officinalis. Indian J. Chem. 35, 459-462
  10. Taesotikul T, Panthong A, Kanjanapothi D, Verpoorte R, Scheffer JJC (2003) Anti-inflammatory, antipyretic and antinociceptive activities of Tabernaemoniana pandacaqui Poir. J. Ethnopharmacol. 84, 31-33 https://doi.org/10.1016/S0378-8741(02)00264-7
  11. Whittle BA. (1964) The use of changes in capillary permeability in mice to distinguish between narcotic and non-narcotic analgesics. Br. J. Pharmacol. Chemother. 22, 246-253