한국환경보건학회지 (Journal of Environmental Health Sciences)

  • 제33권4호
  • /
  • Pages.227-234
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  • 2007
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  • 1738-4087(pISSN)
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  • 2233-8616(eISSN)
한국환경보건학회 (Korean Society of Environmental Health)
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대기오염 노출이 첫 출산아 저체중에 미치는 영향에 관한 연구 -서울지역 1999년~2003년 출생코호트를 중심으로-

Air Pollution Exposure and Low Birth Weight of Firstborn Fetus -A Birth Cohort Study in Seoul, 1999-2003-

  • 조용성 (한양대학교 일반대학원 보건학과) ;
  • 손지영 (한양대학교 일반대학원 보건학과) ;
  • 이종태 (한양대학교 일반대학원 보건학과)
  • Cho, Yong-Sung (Department of Public Health, Graduate School of Hanyang University, Hanyang University) ;
  • Son, Ji-Young (Department of Public Health, Graduate School of Hanyang University, Hanyang University) ;
  • Lee, Jong-Tae (Department of Public Health, Graduate School of Hanyang University, Hanyang University)
  • 발행 : 2007.08.30
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초록

Recent epidemiologic studies show that gestational exposure to air pollution adversely affects pregnancy outcomes including low birth weight in preform birth. In this study, we evaluated the effect of air pollutants on LBW (low birth weight) on firstborn fetus throughout the gestational period using the birth cohort between 1999 and 2003 in Seoul. Using birth cohort data from the National Statistics Office of Korea we identified 288,346 firstborn births (excluded missing data on lack of information for birth weight and discordance between residential and certificated address from a total of 316,451) during 1999 to 2003 with complete covariate (gender, parity, date of birth, gestational age, parental age and educational level, maternal occupation etc.) and maternal residential history data. Our subjects were defined as more than 37 weeks and less than 44 weeks of completed gestation and we identified 5,457 persons (1.89%) by low birth weight (<2.5 kg) in this study. Using logistic regression, we estimated the risk of mean (entire pregnancy and trimester period) air pollution concentrations for CO, $O_3,\;PM_{10},\;NO_2\;and\;SO_2$. In terms of trimester-specific exposure, we found that some air pollutants exposure in each trimester would increase the risk for LBW. Results also showed that the effect size of air pollutants exposure during the first and third trimester is higher than during the second trimester. In all trimester, the estimated risk of LBW was 1.831 (95% CI=1.573-2.132) with unit increase for CO, 1.139 (95% CI=1.107-1.172) for 50, and 1.009 (95% CI=1.001-1.017) for $O_3$. Our results suggest that exposure during the gestation period to relatively low levels of some air pollutants may be associated with a reduction in birth weight on first-born fetus. These findings implicate the effective risk management strategies should be applied to minimize the public health impacts for pregnant women.

키워드

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피인용 문헌

  1. The impacts of air pollution on low birth weight vol.20, pp.3, 2013, https://doi.org/10.1080/13504851.2012.689100