대한의용생체공학회:의공학회지 (Journal of Biomedical Engineering Research)

  • 제28권4호
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  • Pages.556-568
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  • 2007
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  • 1229-0807(pISSN)
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  • 2288-9396(eISSN)
대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
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서포트 벡터 머신을 이용한 심폐소생술 변이의 변화에 따른 제세동 성공률 분석

Analysis of the Likelihood of Successful Defibrillation as a Change of Cardiopulmonary Resuscitation Transition using Support Vector Machine

  • 장승진 (연세대학교 보건과학대학 의공학과) ;
  • 황성오 (연세대학교 원주의과대학 응급의학교실) ;
  • 이현숙 (상지대학교 보건과학대학 한방의료공학과) ;
  • 윤영로 (연세대학교 보건과학대학 의공학과)
  • Jang, Seung-Jin (Department of Bimomedical Engineering, Health and Science College, Yonsei University) ;
  • Hwang, Sung-Oh (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University) ;
  • Lee, Hyun-Sook (Department of Oriental Biomedical Engineering, College of Health Science, Sangji University) ;
  • Yoon, Young-Ro (Department of Bimomedical Engineering, Health and Science College, Yonsei University)
  • 발행 : 2007.08.30
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초록

Unsatisfied results of return of spontaneous circulation (ROSC) estimates were caused by the fact that the predictability of the predictors was insufficient. This unmet estimate of the predictors may be affected by transitional events due to behaviors which occur during cardiopulmonary resuscitation (CPR). We thus hypothesized that the discrepancy of ROSC estimates found in statistical characteristics due to transitional CPR events, may affect the performance of the predictors, and that the performance of the classifier dichotomizing between ROSC and No-ROSC might be different during CPR. In a canine model (n=18) of prolonged ventricular fibrillation (VF), standard CPR was provided with administration of two doses of epinephrine 0 min or 3 min later of the onset of CPR. For the analysis of the likelihood of a successful defibrillation during CPR, Support Vector Classification was adopted to evaluate statistical peculiarity combining time and frequency based predictors: median frequency, frequency band-limited power spectrum, mean segment amplitude, and zero crossing rates. The worst predictable period showed below about 1 min after the onset of CPR, and the best predictable period could be observed from about 1.5 min later of the administering epinephrine through 2.0-2.2 min. As hypothesized, the discrepancy of statistical characteristics of the predictors was reflected in the differences of the classification performance during CPR. These results represent a major improvement in defibrillation prediction can be achieved by a specific timing of the analysis, as a change in CPR transition.

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참고문헌

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