The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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The effect of Environmental Enrichment and Peripheral Nerve Electrical Stimulation on Functional Recovery after Brain in rats

환경강화와 말초신경 전기자극이 뇌손상 백서의 기능회복에 미치는 영향

  • Kim, Sa-Youl (Dongshin University Oriental hospital) ;
  • Kim, Tae-Youl (College of health & welfare, Dongshin University) ;
  • Oh, Myung-Hwa (Department of diet & health management, Dongkang college) ;
  • Kim, Young-Eok (College of health & welfare, Dongshin University) ;
  • Chang, Mee-Kyung (A Physical Therapy Master, Graduate School of Dongshin university) ;
  • Sim, Ki-Cheol (A Physical Therapy Master, Graduate School of Dongshin university) ;
  • Kim, Gye-Yeop (College of health & welfare, Dongshin University)
  • 김사열 (동신대학교 한방병원) ;
  • 김태열 (동신대학교 보건복지대학) ;
  • 오명화 (동강대학 다이어트 건강관리과) ;
  • 김용억 (동신대학교 보건복지대학) ;
  • 장미경 (동신대학교 대학원 물리치료) ;
  • 심기철 (동신대학교 대학원 물리치료) ;
  • 김계엽 (동신대학교 보건복지대학)
  • Published : 2007.02.25
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Abstract

Purpose: To investigate and analyze effects of environmental enrichment(EE) and nerve stimulation that follows in application times with change of functional recovery(1, 3, 7 and 14 days). Methods: Focal ischemic brain injury was produced in 100 Sprauge-Dawley rats through middle cerebral artery occlusion(MCAO). Neurobehavioral assessment were selected, such as tilting plane testing, horizontal wire testing, vestibulomotor function testing and complex neuromotor function test, then they were randomly divided into five groups; Group I : Sham group, Group II: MCAO group, Group III: MCAO and ES group, Group IV: MCAO and EE group, Group V: MCAO and EE and ES group. Results: In neurobehavioral assessment, group V were significantly difference from other groups on between-subject effects. Conclusion: Our findings suggest that in focal ishemic brain injury, combined environmental enrichment and peripheral nerve electrical stimulation is more improved that the improvement of exercise function recovery than non treatment group.

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