An experimental study of HwaYul(火熱) theory on the "SoMunHyunKiWonByungSik(素問玄機原病式)"

"소문현기원병식(素問玄機原病式)"에 기재된 중풍(中風)의 화열(火熱) 병인론(病因論)에 대한 저체온요법을 통한 실험적 고찰

  • Choi, Seong-Hun (Dept. of Anatomy, College of Oriental Medicine, Dongguk University)
  • 최성훈 (동국대학교 한의과대학 해부학교실)
  • Published : 2007.05.31

Abstract

In Oriental medicine, different suggestions regarding how cerebrovascular accident(CVA) may develop have been offered by several physicians. In Jin(金)Yuan(元) dynasty, Liu Wan Su(劉完素) asserted that CVA was not developed by external PungSa(風邪) but internal HwaYul, which was noted in the "SoMunHyunKiWonByungSik". To verify experimentally Liu's HwaYul theory in rats, normothermic control group (37$^{circ}C$) and hypothermic test group (32$^{circ}C$) were subjected to transient middle cerebral artery occlusion(MCAO) of 1hour. In 7days after MCAO, the rats were sacrified and the volume of infarct and the size of edema were measured. The present findings expand our understanding of the pathophysiology as to the CVA which is related to the HwaYul theory.

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