Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Nonspecific Interstitial Pneumonia in a Patient with Ulcerative Colitis

궤양성 대장염에 병발된 비특이적 간질성 폐렴 1예

  • Noh, Young Wook (Department of Internal Medicine, College of Medicine, Ewha Womans University) ;
  • Baik, Eun Kyung (Department of Internal Medicine, College of Medicine, Ewha Womans University) ;
  • Ryu, Yon Ju (Department of Internal Medicine, College of Medicine, Ewha Womans University) ;
  • Kim, Seong-Eun (Department of Internal Medicine, College of Medicine, Ewha Womans University) ;
  • Lee, Jin Hwa (Department of Internal Medicine, College of Medicine, Ewha Womans University) ;
  • Sim, Sung Shin (Department of Radiology, College of Medicine, Ewha Womans University) ;
  • Lee, Shi Nae (Department of Pathology, College of Medicine, Ewha Womans University) ;
  • Chun, Eun Mi (Department of Internal Medicine, College of Medicine, Ewha Womans University)
  • 노영욱 (이화여자대학교 의과대학 내과학교실) ;
  • 백은경 (이화여자대학교 의과대학 내과학교실) ;
  • 류연주 (이화여자대학교 의과대학 내과학교실) ;
  • 김성은 (이화여자대학교 의과대학 내과학교실) ;
  • 이진화 (이화여자대학교 의과대학 내과학교실) ;
  • 심성신 (이화여자대학교 의과대학 방사선학교실) ;
  • 이신애 (이화여자대학교 의과대학 해부병리학교실) ;
  • 천은미 (이화여자대학교 의과대학 내과학교실)
  • Received : 2006.10.26
  • Accepted : 2006.12.28
  • Published : 2007.01.30
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Abstract

Pulmonary complications of ulcerative colitis are relatively uncommon and may present as a variety of disorders. Ulcerative colitis-related interstitial lung disease is extremely rare. There are a few case reports of nonspecific interstitial pneumonia in ulcerative colitis worldwide but none in Korea. We report a patient with ulcerative colitis related biopsy-proven nonspecific interstitial pneumonia, who responded to prednisolone (1 mg/kg) and mesalazine therapy.

궤양성 대장염은 장내 염증으로 국한되지 않고 관절, 피부, 눈, 간 및 담도계 등의 다양한 장외 장기를 흔하게 침범하는 것으로 알려져 있다. 그러나, 궤양성 대장염에 폐질환이 동반되는 경우는 흔치 않고 특히 간질성 폐렴의 병발은 전세계적으로 매우 드물며, 국내에서 수술적 폐생검으로 확진된 비특이적 간질성 폐렴과 동반된 궤양성 대장염 환자는 현재까지 보고 된 바 없다. 저자들은 호흡기 증상 없이 우연히 흉부 방사선촬영의 이상소견으로 입원하여 수술적 폐생검으로 확진된 비특이적 간질성 폐렴과 동시에 활동성 궤양성 대장염을 진단받은 후, prednisolone (1mg/kg)과 함께 mesalazine 병용 치료를 시작해서 비특이적 간질성 폐렴과 궤양성 대장염 모두 호전중인 환자 1예를 경험하여 이를 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

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