Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Graves' Disease Coexistent with Pulmonary Sarcoidosis

폐 사르코이드증에서 동반된 그레이브스병 1예

  • Jo, Ki Won (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Koh, Jang Hyun (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Lee, Mi Young (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Jung, Feel Moon (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Shin, Young Goo (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Yong, Suk Joong (Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Chung, Choon Hee (Department of Internal Medicine, Yonsei University Wonju College of Medicine)
  • 조기원 (연세대학교 원주의과대학 내과학교실) ;
  • 고장현 (연세대학교 원주의과대학 내과학교실) ;
  • 이미영 (연세대학교 원주의과대학 내과학교실) ;
  • 정필문 (연세대학교 원주의과대학 내과학교실) ;
  • 신영구 (연세대학교 원주의과대학 내과학교실) ;
  • 용석중 (연세대학교 원주의과대학 내과학교실) ;
  • 정춘희 (연세대학교 원주의과대학 내과학교실)
  • Received : 2007.02.21
  • Accepted : 2007.04.20
  • Published : 2007.05.30
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Abstract

Sarcoidosis is a multisystemic granulomatous disease with an of unknown etiology, involving bilateral hilar lymphadenopathy, pulmonary, skin and eye lesions. However, involvement of the endocrine system in sarcoidosis is quite rare, and the coexistence of both diseases is extremely unusual. We describe a 60-year-old woman presenting with sarcoidosis and Graves' disease. She was admitted for evaluation of dry cough, dyspnea, palpitation and general weakness. Both thyroid glands were enlarged diffusely. The thyroid function tests showed suppressed serum thyrotropin and an increased thyroid hormone level. The levels of the TSH receptor antibody, anti-thyroglobulin antibody and anti-microsomal antibody were higher than normal. The radionuclide scan($^{131}I$) showed increased iodine uptake. The chest X-ray revealed pulmonary hilar enlargement and high resolution CT showed both hilar lymph nodes enlargement and tiny parenchymal nodules. The transbronchial lung biopsy showed a noncaseating granuloma without necrosis. We report this case of pulmonary sarcoidosis plus Graves' disease with a review of the relevant literatures.

저자들은 사르코이드증 환자에서 그레이브스병이 동반된 1예를 경험하였으며 이는 아직 국내에서 보고된 바 없기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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