Heart Rate Variability of Patients with Major Depressive Disorder under Cognitive and Emotional Stimulus

인지 과제 및 긍정적 정서 유발에 대한 주요 우울장애 환자의 심장 박동 변이(Heart Rate Variability, 이하 HRV) 양상

  • Lee, Chang-Soo (Department of Neuropsychiatry and Stress Research Institute, Inje University Seoul Paik Hospital) ;
  • Kim, De-Sok (Biomedical Imaging and Informatics Lab., School of Engineering, Information and Communications University) ;
  • Jeong, Myeong-Gi (Biomedical Imaging and Informatics Lab., School of Engineering, Information and Communications University) ;
  • Kim, Won (Department of Neuropsychiatry and Stress Research Institute, Inje University Seoul Paik Hospital) ;
  • Woo, Jong-Min (Department of Neuropsychiatry and Stress Research Institute, Inje University Seoul Paik Hospital)
  • 이창수 (인제대학교 의과대학 서울백병원 신경정신과학교실 및 스트레스연구소) ;
  • 김대석 (한국정보통신대학교 공학부 생체의료영상정보 연구실) ;
  • 정명기 (한국정보통신대학교 공학부 생체의료영상정보 연구실) ;
  • 김원 (인제대학교 의과대학 서울백병원 신경정신과학교실 및 스트레스연구소) ;
  • 우종민 (인제대학교 의과대학 서울백병원 신경정신과학교실 및 스트레스연구소)
  • Received : 2007.03.04
  • Accepted : 2007.04.05
  • Published : 2007.04.30

Abstract

Object : This study was designed to assess the change of heart rate variability (HRV) during stimulation test among the patients with major depressive disorder. Methods : 15 patients with major depressive disorder (MDD) and 15 normal controls were enrolled in this study. We sequentially measured HRV at baseline, during cognitive stimuli and emotional stimuli. Results : There are significant differences between the two groups in HRV index, TINN on baseline state and under cognitive stimulus. Conclusion : Stimulation protocol using HRV can be useful in estimating autonomic nervous function.

Keywords