Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of Gami-Daehwangmokdan-tang on the Gout Induced ICR Mice

가미대황목단탕(加味大黃牧丹湯)이 통풍유발 흰쥐에 미치는 영향

  • Eom, Hyun-Sup (Department of Orintal Pathology, College of Oriental Medicine, Dongeui Univiersity)
  • 엄현섭 (동의대학교 한의과대학 병리학교실)
  • Published : 2007.04.25
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Abstract

In order to obtain practical application of Daehwangmokdan-tang gout disease, water extract of Gami-daehwangmokdan-tang(GDMT) added with Lonicera japonica is prepared through decoction and freeze drying. The effects were evaluated with blood sample from ICR mice treated with MSU intra-peritoneal injection 1 time a day, 3 days consecutively. The results were as follows. GDMT decreased BUN, creatinine and C-reactive protein level in serum significantly. But the HDL and LDL cholesterol levels were not changed in spite of positive tendency in HDL cholesterol. Triglyceride and uric acid levels were decreased significantly too. These results show that GDMT can be used effectively against the urate-related gout disease.

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References

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