한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)
- 제20권3호
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- Pages.63-70
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- 2007
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
청기산(淸肌散)이 Th2 세포 분화와 염증에 미치는 영향
Therapeutic Effects of Cheonggisan Extract on Th2 cell differentiation and $NF-kB$ p65 activation
- 발행 : 2007.12.25
초록
Objectives : Atopic dermatitis is a recurrent or chronic eczematous skin disease with severe pruritus. Although the pathogenic mechanisms of atopic dermatitis are yet unknown, recently hyperresponsive Th2 cells in the acute phase are reported as the important mechanisms. Cheonggisan(CGS) is used in oriental clinics for curing acute skin lesions of eczema, atopic dermatitis or urticaria. There have been no studies on the therapeutic mechanism of CGS for curing atopic dermatitis. We aimed to find out the therapeutic mechanism of CGS on atopic dermatitis, so we observed Th2 cell differentiation in EL 4 cells and