태계($KI_3$) 전침의 항산화 효과에 대한 실험적 연구

The Study on the Effect of Electroacupuncture at Taegye($KI_3$) on Anti -oxidation

  • 김성래 (대전대학교 한의과대학 침구학교실) ;
  • 홍권의 (대전대학교 한의과대학 침구학교실) ;
  • 김영일 (대전대학교 한의과대학 침구학교실)
  • Kim, Sung-Lae (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Hong, Kwon-Eui (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Kim, Young-Il (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University)
  • 발행 : 2007.06.20

초록

Objectives : The purpose of this study is to observe the anti-oxidative effects of electroacupuncture at Taegye($KI_3$) in rats. Methods : The methods are measures of experimental items including change of body weight, relative liver weight, level of alblumin, total bilirubin, LDL-cholesterol, LDH, GOT and GPT in blood serum, level of SOD, GSH, catalase, NO and MDA concentration in liver, histological change of liver. Results: 1. The $KI_3$-EA group lost weight in the beginning, and gained it gradually. 2. The liver ratio of the $KI_3$-EA group increased compared to the holder group, without any statistical significance. 3. The SOD activity, Glutathione concentration, and Catalase concentration increased, and the NO concentration and MDA concentration decreased in the $KI_3$-EA group significantly, compared to the holder group. 4. $KI_3$-EA group had more similar density to the normal group, than the holder group. Conclusion : The electroacupuncture application on Kb has anti-oxidation effect, by improving the body defence against the oxidation stress- induced cytotoxicity, and by supressing the oxidative liver damage.

키워드