Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

The Effect of Fel Ursi and Bovis Calculus Pharmacopuncture on Preadipocyte Proliferation and Lipolysis of Adipocyte, Localized Fat Accumulation

웅담과 우황약침이 지방세포 대사에 미치는 영향

  • Cho, Hee-Chul (Korean Medical College, WonKwang University) ;
  • Lee, Si-Hyeong (Korean Medical College, WonKwang University) ;
  • Shin, Jo-Young (Korean Medical College, WonKwang University) ;
  • Kim, Kang-San (Korean Medical College, WonKwang University) ;
  • Cho, Nam-Guen (Korean Medical College, WonKwang University) ;
  • Kwon, Ki-Rok (Department of Acupuncture & Moxibustion, Korean Medical College, Sangji University) ;
  • Lim, Tae-Jin (Devision of Animal resourses and life science, Sangji University)
  • 조희철 (원광대학교 한의과대학) ;
  • 이시형 (원광대학교 한의과대학) ;
  • 신조영 (원광대학교 한의과대학) ;
  • 김강산 (원광대학교 한의과대학) ;
  • 조남근 (원광대학교 한의과대학) ;
  • 권기록 (상지대학교 한의과대학 침구학교실) ;
  • 임태진 (상지대학교 생명지원과학대학 응용동물과학부)
  • Published : 2007.08.20
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Abstract

calculus pharmacopuncture. Porcine skin including fat tissue after treated Fel ursi and Bovis calculus pharmacopuncture by means of the dosage dependent variation are investigated the histologic changes after injection of these pharmacopuncture. Results: Following results were obtained from the preadipocyte proliferation and lipolysis of adipocyte and histologic investigation of fat tissue. 1. Fel ursi and Bovis calculus pharmacopuncture showed the effect of decreased preadipocyte proliferation on the high dosage($1mg/m{\ell}$). 2. Fel ursi pharmacopuncture showed the effect of decreased the activity of glycerol-3-phosphate dehydrogenase (GPDH) on the high dosage($1mg/m{\ell}$) and Bovis calculus pharmacopuncture significantly showed from $0.1mg/m{\ell}$ concentration. 3. Fel ursi pharmacopuncture was not showed the effect of lipolysis, but Bovis calculus pharmacopuncture was increased the effect of lipolysis in all concentration significantly. 4. Investigated the histological changes in porcine fat tissue after treated Fel ursi and Bovis calculus pharmacopuncture, we knew that these pharmacopuncture was showed significant activity to the lysis of cell membranes in all concentration. Conclusion : These results suggest that Fel ursi and Bovis calculus pharmacopuncture efficiently induces diminish proliferation of preadipocyte and lipolysis in adipose tissue.

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