Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)

Korean Society for Clinical Laboratory Science (대한임상검사과학회)
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Comparison of Glass CTAD Tube and Plastic Sodium Citrate Tube for Coagulation Test

혈액응고 검사용 유리 CTAD 채혈관와 플라스틱 Sodium Citrate 채혈관의 비교

  • Kang, Su-Jin (Research Institute and Hospital, National Cancer Center) ;
  • Park, Jeong-Su (Research Institute and Hospital, National Cancer Center) ;
  • Song, Yoon-Kyung (Research Institute and Hospital, National Cancer Center) ;
  • Kong, Sun-Yong (Research Institute and Hospital, National Cancer Center) ;
  • Lee, Do-Hoon (Research Institute and Hospital, National Cancer Center)
  • 강수진 (국립암센터 진단검사의학과) ;
  • 박정수 (국립암센터 진단검사의학과) ;
  • 송윤경 (국립암센터 진단검사의학과) ;
  • 공선영 (국립암센터 진단검사의학과) ;
  • 이도훈 (국립암센터 진단검사의학과)
  • Published : 2007.12.31
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Abstract

We evaluated the newly developed plastic sodium citrate tubes for routine coagulation test by direct comparison with glass citrate theophylline adenosine dipyridamole (CTAD) tubes. Blood was drawn from 100 patients into glass CTAD tubes and plastic sodium citrate tubes. After collection, samples were centrifuged at 1500 ${\times}$g for 15 min at $22^{\circ}C$. Prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen were measured by using the Coagrex-800 (IRC, Japan). We used comparison plot by linear regression model and difference plot graphs to compare the results of the independent measurements of PT, aPTT, fibrinogen between glass CTAD tubes and plastic sodium citrate tubes. On the comparison study between glass CTAD tubes and plastic sodium citrate tubes, the correlation coefficients (R) were 0.99 for PT, 0.97 for aPTT and 0.97 for fibrinogen. This results implicated good correlation of each parameter between two tubes. Although the difference plot graph analysis showed statistically significant differences between glass and plastic tubes for PT, aPTT and fibrinogen, the range of difference was acceptable according to the CLSI/NCCLS guideline. The plastic sodium citrate tubes showed good correlation with the glass CTAD tubes, so it can substitute glass citrate tube for routine coagulation tests.

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