Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Evaluation of Hepatoprotectivte Activity of Citrullus Colocynthis Roots Against $CCl_4$ induced Toxicity in Albino Rats

  • Visen, P.K.S. (Department of Biochemistry, Central Drug Research Institute) ;
  • Saraf, S.A. (Department of Pharmacy, BBDNITM) ;
  • Mukerjee, Alok (Department. of Pharmacy, Allahabad Agricultural Institute-Deemed University)
  • Published : 2007.03.31
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Abstract

Hepatoprotective activity of different extracts of Citrullus colocynthis L. sch. (roots) (cucurbitaceae) was investigated in albino rats by inducing hepatotoxicity with carbon tetrachloride. The alcoholic extract of Citrullus colocynthis sch. 100 mg/kg b.w. has been shown to posses significant hepatoprotective effect by lowering the serum level of transaminases (GPT & GOT), alkaline phosphate (ALP) and bilirubin (P < 0.05 to P < 0.001).

Keywords

References

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