Triterpenoids and Flavonoids Isolated from the Leaves of Alnus firma

사방오리 잎의 Triterpenoid 및 Flavonoid 화합물

  • Yu, Young-Beob (Department of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicine) ;
  • Nakamura, Norio (Institute of Natural Medicine, University of Toyama) ;
  • Miyashiro, Hirotsugu (Institute of Natural Medicine, University of Toyama) ;
  • Hattori, Masao (Institute of Natural Medicine, University of Toyama) ;
  • Park, Jong-Cheol (Department of Oriental Medicine Resources, Sunchon National University)
  • Published : 2007.03.31

Abstract

In this study, three triterpenoids, two steroids and nine flavonoids were isolated from the leaves of Alnus firma Sieb. et Zucc. On the basis of spectroscopic evidences, the structures of these compounds were established as ${\beta}$-amyrin acetate, ${\beta}$-amyrin, ${\beta}$-sitosterol, alnustic acid methyl ester, ${\beta}$-sitosterol glucoside, pinocembrin, alnustinol, quercetin, quercetin-3-O-${\alpha}$-L-arabinofuranoside, quercetin-3-O-${\alpha}$-L -rhamnopyranoside, quercetin-3-O-${\beta}$-D-glucopyranoside, myricetin-3-O-${\beta}$-D-galac-topyranoside, (+)-catechin and (-)-epicatechin.

Keywords

References

  1. 이창복 (1989) 대한식물도감. 269. 향문사, 서울
  2. 이창민, 신민교, 이경순, 안덕균 (1998) 중약대사전. 1837-1838. 도서출판정담, 서울
  3. Choi, S.C. and Kim, M.S. (1998) Studies on the dyeing properties of silk and cotton fabrics with Alnus firma fruit extract. J. of the Korean Fiber Society. 35: 161-173
  4. Yoshinori, A. (1970) Chemical constituents of Alnus firma (Betulaceae). I. Phenylpropane derivatives isolated from Alnus firma. Bulletin of the Chemical Society of Japan. 43: 2223-2229 https://doi.org/10.1246/bcsj.43.2223
  5. Masayasu, N., Takashi, T. and Takashi, K. (1981) Biarylheptanoids and other constituents from wood of Alnus japonica. Phytochemistry. 20: 1097-1104 https://doi.org/10.1016/0031-9422(81)83035-X
  6. Yohsinori, A. (1971) Chemical constituents of Alnus sieboldiana (Betulaceae). II. The isolation and structure of flavonoids and stilbenes, Bulletin of the Chemical Society of Japan. 44: 2761-2766 https://doi.org/10.1246/bcsj.44.2761
  7. Tadashi, A., Shinji, O. and Takayuki, S. (1990) Triterpenoids, diarylheptanoids and their glycosides in the flowers of Alnus species. Phytochemistry. 29: 3611-3614 https://doi.org/10.1016/0031-9422(90)85286-O
  8. Makoto, I., Takashi, T., Gen-Ichiro, N. and Itsuo, N. (1989) Alnusnins A and B from the leaves of Alnus sieboldiana. Phytochemistry. 28: 3179-3184 https://doi.org/10.1016/0031-9422(89)80302-4
  9. Kang, S.S. (1987) $^{13}C$-NMR spectroscopy of amyrins. Kor. J. Pharmacogn. 18: 151-167
  10. Viqar Uddin Ahmad and Atta-Ur-Rhaman (1994) Handbook of natural product data. vol. 2: 163. Elsevier, Amsterdame
  11. Viqar Uddin Ahmad and Atta-Ur-Rhaman (1994) Handbook of natural product data. vol. 2: 21. Elsevier, Amsterdam
  12. Baek, W.S., Woo, W.S. and Yook, C.S. (1988) Studies on the constituents of the root of Angelica flaccida Kommarov. Kor. J. Pharmacogn. 19: 233-238
  13. Kang, S.S., Kim, J.S., You-Choi, H.S. and Han, B.H. (1993) Phytochemical studies on Paeoniae Radix. Kor. J. Pharmacogn. 24: 247-250
  14. Takayuki S., Tadashi A., Toshifumi H., Keiko A., and Yoshinori A. (1979) Structure of alnustic acid, a new secodammarane- type triterpenoic acid from Alnus serrulatioides. Bulletin of the Chemical Society of Japan 52: 1698-1700 https://doi.org/10.1246/bcsj.52.1698
  15. Park, J.C., Young, H.S., Yu, Y.B. and Lee, J.H. (1993) Studies on the chemical components and biological activities of edible plants in Korea (I). Phenolic compounds from the leaves of Cedrela sinensis A. Juss.. Yakhak Hoeji. 37: 306- 310
  16. Mabry, T.J., Markham, K.R. and Thomas, M.B. (1970) The systematic identification of flavonoid. 22-223. Springer, New York
  17. Agrawal, P.K. (1989) Carbon-13 NMR of flavonoids. 337- 337. Elsevier, Amsterdam
  18. Agrawal, P.K. (1989) Carbon-13 NMR of flavonoids. 156. Elsevier, Amsterdam
  19. Agrawal, P.K. (1989) Carbon-13 NMR of flavonoids. 128. Elsevier, Amsterdam
  20. Lee, Y.A. and Lee, M.W. (1995) Tannins from Rubus coreanum. Kor. J. Pharmacogn. 26: 27-30