Journal of Pharmacopuncture (대한약침학회지)

KOREAN PHARMACOPUNCTURE INSTITUTE (대한약침학회)
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인삼, 한국 및 중국산 산양삼의 간 보호 효능에 관한 실험적 연구

  • Kim, Young-Jin (Dept. of Acup & Moxibustion, College of Oriental Medicine, Sangji University) ;
  • Park, Hee-Soo (Dept. of Acup & Moxibustion, College of Oriental Medicine, Sangji University) ;
  • Kwon, Ki-Rok (Dept. of Acup & Moxibustion, College of Oriental Medicine, Sangji University) ;
  • Kim, Ho-Hyun (Dept. of Physiology, College of Oriental Medicine, Semyung University)
  • 김영진 (상지대학교 한의과대학 침구학교실) ;
  • 박희수 (상지대학교 한의과대학 침구학교실) ;
  • 권기록 (상지대학교 한의과대학 침구학교실) ;
  • 김호현 (세명대학교 한의과대학 생리학교실)
  • Published : 2007.02.28
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Abstract

Objectives : This study was aimed at investigating liver protection mechanism of Cultivated Ginseng and Cultivated Wild Ginseng of Korean and Chinese by inducing liver toxicity through $CCl_4$ and t-BHP in mice and evaluated serological findings. Methods : Experiment groups was categorized into untreated normal group, treated control group, and orally administered Cultivated Ginseng and Cultivated Wild Ginseng of Korean and Chinese experimental groups. At the termination of experiment, gross examination of the liver as well as Total bilirubin, AST, and ALT contents in the serum were evaluated. Results : 1. In the $CCl_4$ induced acute hepatotoxicity test, total bilirubin, AST and ALT didn't show significant differences between the control and experimental groups. 2. In the t-BHP induced acute hepatotoxicity test, total bilirubin, AST and ALT didn't show significant differences between the control and experimental groups. Conclusion : Taken together, Cultivated Ginseng and Cultivated Wild Ginseng of Korean and Chinese cannot be effectively used for recovering the liver functions in acute hepatotoxicity tests using $CCl_4$ and t-BHP. Further researches, for example treated long period, must be tried to verify the efficacies.

Keywords

References

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