Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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A CASE REPORT OF KIKUCHI-FUJIMOTO DISEASE

Kikuchi-Fujimoto Disease의 치험례

  • Jang, Tae-Hwa (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kim, Jin-Wook (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kwon, Tae-Geon (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Jang, Hyung-Jung (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kim, Chin-Soo (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Lee, Sang-Han (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
  • 장태화 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 김진욱 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 권대근 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 장현중 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 김진수 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 이상한 (경북대학교 치과대학 구강악안면외과학교실)
  • Published : 2007.11.30
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Abstract

Kikuchi-Fujimoto disease is a rare disease first described in 1972 by Kikuchi and Fujimoto et al. The disease is described as a benign and unusual self-limiting histiocytic necrotizing lymphadenitis of unknown origin, which is characterized histologically by necrotic foci surrounded by histiocytic aggregates. is usually manifested with lymphadenopathy and high fever. This disease mostly affects young Asian women between 20 and 30 years of age and has rarely been reported in children. Main symptoms are indolent or light tender, enlarged lymph nodes in the neck area. The correct diagnosis requires the histologic examination of the lymph node. Kikuchi-Fujimoto disease is easily confused histologically and clinically with lymphoma and systemic lupus erythematosis histologically and clinically. Although it is an uncommon cause of fever of unknown origin, early recognition of KFD is very important and will minimize potentially harmful and unnecessary evaluations and treatments. We reported a case, a 23-year old man who had Kikuchi-Fujimoto disease with a literature review.

본 과에서는 우측 악하부의 부종 및 동통을 주소로 내원한 환자를 초기에 우측 악하부 및 협부 농양으로 진단하고 절개 및 배농술을 시행하였으나 증상의 호전이 없고 고열과 림프절 비대가 지속적으로 관찰되었다. 이에 저자 등은 비대된 임프절의 적출술과 다양한 검사를 통하여 괴사성 림프절염을 조직학적으로 확인하고 최종적으로 Kikuchi Fujimoto Disease로 확진하였다. Kikuchi-Fujimoto Disease는 임파선 비대와 고열이 동반되는 원인 불명의 괴사성 임파선염으로 특징지워지는 질환으로서, 적출생검을 통해 증상이 사라지는 경우가 많으므로 상기와 같은 증상이 동반된 환자의 경우 악성 림프종이나 전신성 홍반성 루푸스등의 여러 질환과의 감별진단을 통하여 정확한 치료를 시행하는 것이 추천된다.

Keywords

References

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