Prader-Willi Syndrome 환자에서 여성형 유방의 치험례

Treatment of Gynecomatia in a Patient with Prader-Willi Syndrome

  • 강낙헌 (충남대학교 의과대학 성형외과학교실) ;
  • 송승한 (충남대학교 의과대학 성형외과학교실) ;
  • 오상하 (충남대학교 의과대학 성형외과학교실)
  • Kang, Nak Heon (Department of Plastic & Reconstructive Surgery, College of Medicine, Chungnam National University) ;
  • Song, Seung Han (Department of Plastic & Reconstructive Surgery, College of Medicine, Chungnam National University) ;
  • Oh, Sang Ha (Department of Plastic & Reconstructive Surgery, College of Medicine, Chungnam National University)
  • 투고 : 2006.11.20
  • 발행 : 2007.09.10

초록

Purpose: Prader-Willi Syndrome(PWS) is a congenital chromosomal disorder characterized by compulsive and early development of obesity. Obesity is identified as the main cause of morbidity in PWS individuals. Also, body change for rapid weight gain, such as gynecomastia, can cause considerable functional and psychological trauma, We corrected successfully gynecomastia in PWS patient, so we reported our experience of surgical method and literature reviews. Methods: A 16-year-old male patient presented with gynecomastia. He was diagnosed as with PWS at pediatric department. We performed reduction mammaplasty using inferior pedicle and Wise pattern. Excision amount was 1350g in right breast and 1415g in left breast. Also, we managed upper and lateral fullness of breast with liposuction. Results: There were no specific complications, such as hematoma, infection, nipple-areola complex necrosis, and so on. Also, aesthetic and functional outcome was acceptable Conclusion: We experienced successful correction of gynecomastia in PWS patient, and found advantages of conventional reduction mammaplasty using inferior pedicle and Wise pattern at this specific situation.

키워드

참고문헌

  1. Gunay-Aygun M, Schwartz S, Heeger S: The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria. Pediatrics 108: 92, 2001 https://doi.org/10.1542/peds.108.5.e92
  2. Cassidy SB, Forsythe M, Heeger S, Nicholls RD, Schork N, Benn P, Schwartz S: Comparison of phenotype between patients with Prader-Willi syndrome due to deletion 15q and uniparental disomy 15. Am J Med Genet 68: 433, 1997 https://doi.org/10.1002/(SICI)1096-8628(19970211)68:4<433::AID-AJMG12>3.0.CO;2-T
  3. Lindgren AC, Barkeling B, Hagg A, Ritzen EM, Marcus C, Rossner S: Eating behavior in Prader-Willi syndrome, normal weight, and obese control groups. J Pediatr 137: 50, 2000 https://doi.org/10.1067/mpd.2000.106563
  4. Papavramidis ST, Kotidis EV, Gamvros O: Prader-Willi syndrome-associated obesity treated by biliopancreatic diversion with duodenal switch. Case report and literature review. J Pediatr Surg 41: 1153, 2006 https://doi.org/10.1016/j.jpedsurg.2006.01.065
  5. Hodgson EL, Fruhstorfer BH, Malata CM: Ultrasonic liposuction in the treatment of gynecomastia. Plast Reconstr Surg 116: 646, 2005 https://doi.org/10.1097/01.prs.0000173441.57812.e8
  6. Persichetti P, Berloco M, Casadei RM, Marangi GF, Di LelIa F, Nobili AM: Gynecomastia and the complete circumareolar approach in the surgical management of skin redundancy. Plast Reconstr Surg 107: 948, 2001 https://doi.org/10.1097/00006534-200104010-00007
  7. Mandrekas AD, Zambacos GJ, Anastasopoulos A, Hapsas DA: Reduction mammaplasty with the inferior pedicle technique: early and late complications in 371 patients. Br J Plast Surg 49: 442, 1996 https://doi.org/10.1016/S0007-1226(96)90027-2
  8. Wagner DS, Alfonso DR: The influence of obesity and volume of resection on success in reduction mammaplasty: an outcomes study. Plast Reconstr Surg 115: 1034, 2005 https://doi.org/10.1097/01.PRS.0000154213.06888.F9