공업화학 (Applied Chemistry for Engineering)

  • 제18권1호
  • /
  • Pages.54-57
  • /
  • 2007
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  • 1225-0112(pISSN)
  • /
  • 2288-4505(eISSN)
한국공업화학회 (The Korean Society of Industrial and Engineering Chemistry)
권호 표지

Octasubstituted Cyclotetraphosphazene으로부터 Vesicle의 형성

Preparation of Vesicles Using Octasubstituted Cyclotetraphosphazene

  • 신영재 (한국과학기술원 전자전산학과) ;
  • 박철순 (충북대학교 화학과.기초과학연구소) ;
  • 김주연 (충북대학교 화학과.기초과학연구소) ;
  • 김세라 (충북대학교 화학과.기초과학연구소) ;
  • 신재섭 (충북대학교 화학과.기초과학연구소)
  • Shin, Young Jae (Department of Electrical Engineering and Computer Science, KAIST) ;
  • Park, Chul Soon (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University) ;
  • Kim, Ju Youn (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University) ;
  • Kim, Se Ra (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University) ;
  • Shin, Jae Sup (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University)
  • 투고 : 2006.10.26
  • 심사 : 2007.01.25
  • 발행 : 2007.02.10
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초록

Octachlorocyclotetraphosphazene을 사용하여 cyclotetraphosphazene 구조를 내부에 갖고 외부로 8개의 사슬 구조를 갖는 cyclotetraphosphazene 유도체를 합성하였다. 그리고 이 유도체와 콜레스테롤을 사용하여 vesicle을 형성시켰으며, TEM을 이용해서 이 vesicle의 형태를 살펴보고, encapsulation 효율 등을 알아보았다. 이 vesicle의 안정도는 dihexadecylphosphate를 첨가함에 의해서 크게 향상되었다.

A cyclotetraphosphazene derivative having eight chains was synthesized from octachlorocyclotetraphosphazene, which was employed along with cholesterol for the preparation of vesicles. The resulting vesicles were characterized by TEM and encapsulation efficiency. The stability of the vesicles was enhanced in the presence of dihexadecylphosphate.

키워드

과제정보

연구 과제 주관 기관 : 중소기업청

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