Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
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The Association of Lead Biomarkers of Lead Workers with Airborne Lead Concentration in Lead Industries

납 사업장의 공기 중 납 농도 및 납 노출 근로자들의 납 관련 생물학적 노출 지표의 관련성에 관한 조사

  • Kim, Nam-Soo (Institute of Industrial Medicine, Soonchunhyang University) ;
  • Kim, Jin-Ho (Institute of Industrial Medicine, Soonchunhyang University) ;
  • Jang, Bong-Ki (Department of Environmental Health Science, Soonchunhyang University) ;
  • Kim, Hwa-Sung (Institute of Industrial Medicine, Soonchunhyang University) ;
  • Ahn, Kyu-Dong (Institute of Industrial Medicine, Soonchunhyang University) ;
  • Lee, Byung-Kook (Institute of Industrial Medicine, Soonchunhyang University)
  • 김남수 (순천향대학교 산업의학연구소) ;
  • 김진호 (순천향대학교 산업의학연구소) ;
  • 장봉기 (순천향대학교 환경보건학과) ;
  • 김화성 (순천향대학교 산업의학연구소) ;
  • 안규동 (순천향대학교 산업의학연구소) ;
  • 이병국 (순천향대학교 산업의학연구소)
  • Received : 2006.09.25
  • Accepted : 2007.01.31
  • Published : 2007.03.30
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Abstract

This study was designed to investigate the difference of airborne lead concentration by type of lead industries and type of lead exposure and to evaluate their association with lead biomarkers of lead workers in 11 lead using industries. Total of 182 lead workers (male: 167, female: 15) from 11 lead industries were participated for this study from March, 2004 to August, 2005. Airborne lead concentration were measured by representative personal sampling of workers in each unit workplace and applied same concentration value to the workers in the same unit workplace who did not measure their airborne lead with personal air sampling. Tibia lead, blood lead, zinc protoporphyrin in whole blood, ${\delta}$-aminolevulinic acid in urine, hemoglobin and hematocrit were selected as study variables of indices of lead exposure. Information about type of lead exposure (fume or non-fume other), age, work duration, smoking & drinking habit were also collected. Significant differences were seen in the means of zinc protoporphyrin, blood lead and tibia lead in lead workers by different airborne lead concentration in workplace. While blood lead and tibia lead in lead workers were significantly higher in secondary smelting than other types of lead industries, zinc protoporphyrin, ${\delta}$-aminolevulinic acid in urine and airborne lead concentration were significantly higher in litharge manufacturing. While the mean blood lead was significantly higher in the lead workers working in fume type unit workplace than those of non-fume lead workers, the mean airborne lead concentration of fume workers was significantly lower than non-fume lead workers. In the multiple regression analysis of airborne lead concentration and the type of lead exposure on tibia lead and lead exposure indices after adjustment of related covariates, airborne lead concentration was statistically significantly associated with blood lead and tibia lead, but the type of lead exposure was only associated with blood lead. To verify the causal association of airborne lead concentration on blood lead and tibia lead, further studies are needed.

Keywords

References

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