Isolated Cerebral Mucormycosis

  • Han, Seong-Rok (Department of Neurosurgery, Ilsan Paik Hospital College of Medicine Inje University) ;
  • Choi, Chan-Young (Department of Neurosurgery, Ilsan Paik Hospital College of Medicine Inje University) ;
  • Joo, Mee (Department of Pathology, Ilsan Paik Hospital College of Medicine Inje University) ;
  • Whang, Choong-Jin (Department of Neurosurgery, Ilsan Paik Hospital College of Medicine Inje University)
  • Published : 2007.11.30

Abstract

Isolated cerebral mucoromycosis, without rhino-orbital focus, is an extremely rare but life-threatening infection of central nervous system that most commonly found in intravenous drug abuser. We present a case of isolated cerebral mucormycosis diagnosed by open biopsy and treated with amphotericin B. The patient has returned to independent living.

Keywords

References

  1. Alleyne CH Jr, Vishteh AG, Spetzler RF, Detwiler PW : Long-term survival of a patient with invasive cranial base rhinocerebral mucormycosis treated with combined endovascular, surgical, and medical therapies: case report. Neurosurgery 45 : 1461-1464, 1999 https://doi.org/10.1097/00006123-199912000-00037
  2. Blazquez R, Pinedo A, Cosin J, Miralles P, Lacruz C, Bouza E : Nonsurgical cure of isolated cerebral mucormycosis in an intravenous drug user. Eur J Clin Microbiol Infect Dis 15 : 598-599, 1996 https://doi.org/10.1007/BF01709370
  3. Blitzer A, Lawson W, Meyers BR, Biller HF : Patient survival factors in paranasal sinus mucormycosis. Laryngoscope 90: 635-648, 1980
  4. Cheema SA, Amin F : Five cases of rhinocerebral mucormycosis: Br J Oral maxillofac Surg 12 : 2-3, 2005
  5. Escobar A, Del Brutto OH : Multiple brain abscesses from isolated cerebral mucormycosis. J Neurol Neurosurg Psychiatry 53 : 431-433, 1990 https://doi.org/10.1136/jnnp.53.5.431
  6. Gollard R, Rabb C, Larsen R, Chandrasoma P : Isolated cerebral mucormycosis: case report and therapeutic considerations. Neurosurgery 34: 174-177, 1994 https://doi.org/10.1227/00006123-199401000-00026
  7. Hamilton JF, Bartkowski HB, Rock JP : Management of CNS mucormycosis in the pediatric patient. Pediatr Neurosurg 38: 212-215, 2003 https://doi.org/10.1159/000069101
  8. Kwak SW, Kim JT, Chung DS : Massive cerebral infarction due to rhinocerebral mucormycosis. J Korean Neurosurg Soc 39 : 455-458, 2006
  9. Orguc S, Yuceturk AV, Demir MA, Goktan C : Rhinocerebral mucormycosis : perineural spread via the trigeminal nerve. J Clin Neurosci 12 : 484-486, 2005 https://doi.org/10.1016/j.jocn.2004.07.015
  10. Ruoppi P, Dietz A, Nikanne E, Seppa J, Markkanen H, Nuutinen J: Paranasal sinus mucormycosis: a report of two cases. Acta Otolaryngol 121: 948-952, 2001 https://doi.org/10.1080/00016480127363
  11. Siddiqi SU, Freedman JD : Isolated central nervous system mucormycosis : South Med J 87: 997-1000, 1994 https://doi.org/10.1097/00007611-199410000-00006
  12. Verma A, Brozman B, Petito CK : Isolated cerebral mucormycosis: report of a case and review of the literature. J Neurol Sci 240 : 65-69, 2006 https://doi.org/10.1016/j.jns.2005.09.010
  13. Weprin BE, Hall WA, Goodman J, Adams GL: Long-term survival in rhinocerebral mucormycosis: Case report. J Neurosurg 88 : 570-575, 1998 https://doi.org/10.3171/jns.1998.88.3.0570