Three Terpenes and One Phenolic Compound from Sasa borealis

  • Lee, Jun (College of Pharmacy and Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Jeong, Yeon-Hee (College of Pharmacy and Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Jang, Dae-Sik (Department of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicine) ;
  • Seo, Eun-Kyoung (College of Pharmacy and Center for Cell Signaling & Drug Discovery Research, Ewha Womans University)
  • 발행 : 2007.03.30

초록

Four compounds of previously known structures, friedeline (1), 3-hydroxyglutinol (2), p-hydroxy-benzealdehyde (3), and squalene (4) were obtained from the n-hexane- and EtOAc-soluble fractions of the dried whole plants of Sasa borealis. The structures of 1-4 were identified by the interpretation of their spectroscopic data including 1D and 2D NMR as well as by comparison with previously reported values. This is the first report on the isolation of compounds 1-4 from S. borealis.

키워드

참고문헌

  1. Akao Y, Seki N, Nakagawa Y, Yi H, Matsumoto K, Ito Y, Ito K, Funaoka M, Maruyama W, Naoi M, and Nozawa Y (2004) A highly bioactive lignophenol derivative from bamboo lignin exhibits a potent activity to suppress apoptosis induced by oxidative stress in human neuroblastoma SH-SY5Y cells. Bioorg Med Chem 12, 4791-4801 https://doi.org/10.1016/j.bmc.2004.07.022
  2. Akihisa T, Yamamoto K, Tamura T, Kimura Y, Iida T, Nambara T, and Chang FC (1992) Triterpenoid ketones from Lingnania chungii McClure: arborinone, friedelin and glutinone. Chem Pharm Bull 40, 789-791 https://doi.org/10.1248/cpb.40.789
  3. Chang CW, Wu TS, Hsieh YS, Kuo SC, and Chao PDL (1999) Terpenoids of Syzygium formosanum. J Nat Prod 62, 327-328 https://doi.org/10.1021/np980313w
  4. Frahn JL and Illman RJ (1973) Separation of some indolylalkylamines from their metho cation derivatives using neutral polystyrene resin. Application to the alkaloids of Phalaris tuberosa (gramineae). J Chromatogr 87, 187- 191 https://doi.org/10.1016/S0021-9673(01)91532-8
  5. He HP, Cai Y, Sun M, and Corke H (2002) Extraction and purification of squalene from Amaranthus Grain. J Agric Food Chem 50, 368-372 https://doi.org/10.1021/jf010918p
  6. Jang DS, Han AR, Park G, Jhon GJ, and Seo EK (2004) Flavonoids and aromatic compounds from the rhizomes of Zingiber zerumbet. Arch Pharm Res 27, 386-389 https://doi.org/10.1007/BF02980078
  7. Jautelat M, Grutzner JB, and Roberts JD (1970) Naturalabundance carbon-13 nuclear magnetic resonance spectra of terpenes and carotenes. Proc Natl Acad Sci USA 65, 288-292
  8. Jeong YH, Lee J, Kwon Y, and Seo EK (2006) Reversephase HPLC method for identification of diastereomeric constituents from Sasa borealis. Yakhak Hoechi 50, 21- 25
  9. Jeong YH, Nam JW, Lee NY, Seo EK, and Kwon Y (2005) Isolation and structural identification of minor constituents from Sasa borealis. Nat Prod Sci 11, 170-173
  10. Koh K and Jeon ES (2003) Ferns, Fern-Allies and seedbearing plants of Korea. pp. 736-740, Iljinsa, Seoul
  11. Leong YW and Harrison LJ (1999) (20R,23E)-eupha-8,23- diene-3b,25-diol from Tripetalum cymosum. Phytochem 50, 849-857 https://doi.org/10.1016/S0031-9422(98)00565-2
  12. Lin YL, Kuo YH, and Chen YL (1989) Two new clerodane- type diterpenoids, clerodinins A and B, from Clerodendron brachyanthum Schauer. Chem Pharm Bull 37, 2191-2193 https://doi.org/10.1248/cpb.37.2191
  13. Nakajima Y, Yun YS, and Kunugi A (2003) Six new flavonolignans from Sasa veitchii (Carr.) Rehder. Tetrahedron 59, 8011-8015 https://doi.org/10.1016/j.tet.2003.08.026
  14. Namba T and Ki HB (1982) Pharmacognogical studies on the crude drug 'Zhu'-ye' and Nambusaceous plants (VII). On the botanical origins of the folk medicine 'Kuma-zasa' on the Japanese markets and the comparative anatomical studies of the leaves of the Genus Sasa. Shoyakugaku Zasshi 36, 43-54
  15. Ohmoto T, Ikuse M, and Natori S (1970) Triterpenoids of the Gramineae. Phytochem 9, 2137-2148 https://doi.org/10.1016/S0031-9422(00)85379-0
  16. Ohmoto T, Uzawa S, and Tanaka R (1974) Triterpenoids and the related compounds from gramineae plants. Shoyakugaku Zasshi 28, 1-6
  17. Ren M, Reilly RT, and Sacchi N (2004) Sasa health exerts a protective effect on Her2/NeuN mammary tumorigenesis. Anticancer Res. 24, 2879-2884
  18. Wassel G, El-Menshawi B, Saeed A, Mahran G, and Reisch J (1987) New sources of pyrrolizidine alkaloids: genus Cordia (Ehretiaceae) and Schismus (Gramineae). Sci Pharm 55, 163-166
  19. Yoon KD, Kim CY, and Huh H (2000) The flavone glycosides of Sasa borealis. Saengyak Hakhoechi 31, 224-227