Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Apocarotenoids from an Association of Two Marine Sponges

  • Shinde, Pramod B. (College of Pharmacy, Pusan National University) ;
  • Kim, Mi-Ae (College of Pharmacy, Pusan National University) ;
  • Son, Byeng-Wha (Department of Chemistry, Pukyong National University) ;
  • Lee, Chong-O. (Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology) ;
  • Jung, Jee-H. (College of Pharmacy, Pusan National University)
  • Published : 2007.12.31
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Abstract

Bioactivity-guided fractionation of MeOH extract of an association of two sponges, Jaspis sp. and Poecillastra sp. resulted in isolation of four apocarotenoids (1 - 4). Their structures were determined on the basis of MS and NMR spectroscopic analyses and by direct comparison with those of reported. This is the first report on isolation of these compounds from any sponge. Isolated metabolites were evaluated for cytotoxicity against a small panel of solid human tumor cell lines.

Keywords

References

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