Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Cytotoxic and Antibacterial Activities of Gossypin

  • Chamundeeswari, D. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University) ;
  • Sukumar, Ethirajan (Department of Applied Sciences, Higher College of Technology) ;
  • Amar, K. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University) ;
  • Reddy, N. Brahmananda (Sri Ramachandra College of Pharmacy, Sri Ramachandra University) ;
  • Kumar, I. Anil (Sri Ramachandra College of Pharmacy, Sri Ramachandra University) ;
  • Chowdry, B.V. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University) ;
  • Samatha, K. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University)
  • Published : 2007.12.31
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Abstract

Gossypin, a naturally occurring polyhydroxy flavonoid, when subjected to in vitro cytotoxic screening against vero cell lines exhibited 68.75% inhibition at a concentration of $1000{\mu}g$. When tested against five bacteria and five fungi, the flavone derivative showed a moderate activity against Staphylococcus aureus and Escherichia coli, mild inhibition against Pseudomonas aerugenosa and Salmonella typhi and no activity against any of the tested fungi, in the concentrations studied.

Keywords

References

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