DOI QR코드

DOI QR Code

Synthesis and Characterization of Alkyl Methacrylate-based Microgels by Experimental Design Method

  • Lee, Young-Keun (Industry-Academy Cooperation Foundation, RIC, Natural Cosmetics and Perfumery Institute, Soon Chun Hyang University) ;
  • Jin, Fan-Long (Department of Materials Engineering, School of Chemical and Materials Engineering, Jilin Institute of Chemical Technology) ;
  • Park, Soo-Jin (Department of Chemistry, Inha University)
  • Published : 2007.09.20

Abstract

In this work, alkyl methacrylate-based microgels were synthesized by an experimental design method, and their sebum absorption characteristics were investigated. The results of fractional factorial experimentation indicated that the cross-linking agent content, solvent content, and stirring speed were the main parameters in the synthesis of the microgels. The suitable synthesis conditions were determined by the response surface design method. Through a study of the monomer and solvent effects, it was confirmed that the microgel shows the highest sebum absorption ratio when t-butyl methacrylate is used as a monomer or when acetone is used as a solvent. The optimal microgel synthesis conditions for cosmetic application were determined, and the resulting microgel had a mean particle size of 4.7 μm and a sebum absorption ratio of 435%.

Keywords

References

  1. Okubo, M.; Yonehara, H.; Yamashita, T. Colloid Polym. Sci. 2000, 278, 1007 https://doi.org/10.1007/s003960000365
  2. Bodugoz, H.; Guven, O. J. Appl. Polym. Sci. 2002, 83, 349 https://doi.org/10.1002/app.2250
  3. Li, W. H.; Stover, H. D. H. J. Polym. Sci. Part A: Polym. Chem. 1999, 37, 2899 https://doi.org/10.1002/(SICI)1099-0518(19990801)37:15<2899::AID-POLA23>3.0.CO;2-8
  4. Li, W. H.; Li, K.; Stover, H. D. H. J. Polym. Sci. Part A: Polym. Chem. 1999, 37, 2295 https://doi.org/10.1002/(SICI)1099-0518(19990715)37:14<2295::AID-POLA2>3.0.CO;2-J
  5. Oh, B.; Jung, W. I.; Kim, D. W.; Rhee, H. W. Bull. Korean Chem. Soc. 2002, 23, 683 https://doi.org/10.1007/BF02706815
  6. Park, Y. T.; Lee, S. G.; Cheong, J. J. Bull. Korean Chem. Soc. 1997, 18, 1135
  7. Jun, J. B.; Uhm, S. Y.; Suh, K. D. Macromol. Chem. Phys. 2003, 204, 451 https://doi.org/10.1002/macp.200390012
  8. Park, S. J.; Lee, Y. M.; Hong, S. K. Colloid Surface B 2006, 47, 211 https://doi.org/10.1016/j.colsurfb.2005.12.001
  9. Bai, F.; Li, R.; Yang, X.; Li, S.; Huang, W. Polym. Int. 2006, 55, 319 https://doi.org/10.1002/pi.1963
  10. Saikia, P. J.; Lee, J. M.; Lee, B. H.; Choe, S. J. Polym. Sci. Part A: Polym. Chem. 2007, 45, 348 https://doi.org/10.1002/pola.21834
  11. Oh, B.; Sun, Y. K.; Kim, D. W. Bull. Korean Chem. Soc. 2001, 22, 1136
  12. Gabrielsson, J.; Lindberg, N. O.; Lundstedt, T. J. Chemometrics 2002, 16, 141 https://doi.org/10.1002/cem.697
  13. Park, S. J.; Kim, K. S. Colloids Surf. B 2005, 43, 138 https://doi.org/10.1016/j.colsurfb.2005.04.006
  14. Sedlmeyer, F.; Daimer, K.; Rademacher, B.; Kulozik, U. Colloids Surf. B 2003, 31, 13 https://doi.org/10.1016/S0927-7765(03)00039-0
  15. Dondos, A.; Papanagopoulos, D. J. Polym. Sci. Part B: Polym. Phys. 2003, 41, 707 https://doi.org/10.1002/polb.10417
  16. Caykara, T.; Dogmus, M.; Kantoglu, O. J. Polym. Sci. Part B: Polym. Phys. 2004, 42, 2586 https://doi.org/10.1002/polb.20129

Cited by

  1. Effect of Hydrogenated Lecithin on Cytotoxicity of Liposome vol.30, pp.2, 2007, https://doi.org/10.5012/bkcs.2009.30.2.339
  2. Effect of Lecithin on Dermal Safety of Nanoemulsion Prepared from Hydrogenated Lecithin and Silicone Oil vol.30, pp.4, 2007, https://doi.org/10.5012/bkcs.2009.30.4.821