Biomedical Science Letters (대한의생명과학회지)

The Korean Society for Biomedical Laboratory Sciences (대한의생명과학회)
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Determinant of Arterial Stiffness in Young Adults

  • Jo Yoon-Kyung (Department of Clinical Laboratory Science, Dongnam Health College) ;
  • Jeon Justin Y. (Department of Sport and Leisure Studies, Yonsei University) ;
  • Kim Eun-Sung (Department of Sport and Leisure Studies, Yonsei University) ;
  • Jekal Youn-Suk (Department of Sport and Leisure Studies, Yonsei University) ;
  • Eom Yong-Bin (Devision of Forensic Medicine, National Institute of Scientific Investigation) ;
  • Im Jee-Aee (Department of Laboratory Medicine, MizMedi Hospital)
  • Published : 2006.09.01
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Abstract

Cardiovascular disease (CVD) risk factors may be acting several decades before CVD becomes manifest. Data from young subjects may be valuable in further elucidating at this issue. We evaluated the association between baPWV (brachial-ankle pulse wave velocity) and cardiovascular risk factors in apparently healthy young adults. A total of 46 male and 91 female adolescents aged $18{\sim}25 years$ were studied. baPWV increased in a dose-responsive manner as the number of metabolic syndrome components. In both gender groups, baPWV was positively correlated with age. In males, waist, circumference total cholesterol, and LDL-cholesterol were positively correlated with baPWV, and in females, blood pressure (BP) was positively correlated with baPWV. Age, gender, mean BP, and Homeostasis model assessment insulin resistance (HOMA-IR) were found to be independent factors associated with baPWV levels. In conclusion, mean BP, age, gender, and HOMA-IR were associated with baPWV in young adults. This result suggests that multiple cardiovascular risk factors may be associated with an increased risk of arterial stiffness in young adults.

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