Environmental Mutagens and Carcinogens (한국환경성돌연변이발암원학회지)

Korean Environmental Mutagen Society (한국환경성돌연변이발암원학회)
권호 표지

Antioxidant and Antimicrobial Activities of Seaweed, Ulva lactuca

갈파래 (Ulva lactuca) 추출물의 항균 및 항산화 효과

  • Kim In-Hae (Department of Pharmaceutical Engineering, Collage of Medical Life Science, Silla University) ;
  • Lee Hee-Hyun (Department of Bioscience and Biotechnology, Collage of Engineering, Silla University) ;
  • Jang Jeong-Su (Binex Co.) ;
  • Lee Sang-Hyun (Department of Pharmaceutical Engineering, Collage of Medical Life Science, Silla University) ;
  • Ha Jong-Myung (Department of Pharmaceutical Engineering, Collage of Medical Life Science, Silla University) ;
  • Ha Bae-Jin (Department of Pharmaceutical Engineering, Collage of Medical Life Science, Silla University) ;
  • Lee Jae-Hwa (Department of Pharmaceutical Engineering, Collage of Medical Life Science, Silla University)
  • 김인혜 (신라대학교 의생명과학대학 제약공학과) ;
  • 이희현 (신라대학교 공과대학 생명공학과) ;
  • 장정수 ((주) 바이넥스) ;
  • 이상현 (신라대학교 의생명과학대학 제약공학과) ;
  • 하종명 (신라대학교 의생명과학대학 제약공학과) ;
  • 하배진 (신라대학교 의생명과학대학 제약공학과) ;
  • 이재화 (신라대학교 의생명과학대학 제약공학과)
  • Published : 2006.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

Our investigation of the seaweed extracts, Ulva lactuca. The biological activities antioxidant, antimicrobial activity, antifungal and haemolytic activity of ethy-ether and ethyl-acetate extracts from the seaweed, Ulva lactuca were investigated. They were separately extracted using ethyl-ether and ethyl-acetate from dried samples at room temperature and freeze dried. Seaweed extracts were found to cause significant free radical scavenging effects on DPPH (1,1-diphenyl-2-picrylhydrazyl). Seaweed extracts had not significant haemolytic activity against human erythrocyte. This extracts exhibited in vitro broad-spectrum antimicrobial activity of gram-negative, gram-positive bacteria and without antifungal activity.

Keywords

References

  1. Ayako, Y., Koichi, Y. and Keiichi, O. (1982) Iodine distribution in blades of several laminarias grown in the same sea area. Bull Japan Soc. Sci. Fish, 58, 1373-1379
  2. Beuchat, G.C. and Golden, D.A. (1989) Antimicrobial occuring naturally in foods. Food Technol., 43, 134-142
  3. Bin, J.-H., Kim, H.-D. and Ryu, B.-H. (1996) Anticomplementary activities of rhamman sulfate extracted from Monastromsa nitidum. Korean J. Food & Nutr., 4, 490-495
  4. Gibson, B.W., Tang, D.Z., Mandrell, R., Kelly, M. and Spindel, R. R. (1991). Bombinin-like peptides with antimicrobial activity from skin secretions of asian toad, Bomina orientails. J. Biol. Chem, 266, 23103-23111
  5. Ito, H. and Sugimura, M. (1976) Antitumor polysaccharide fraction from Sargassume thunbergii. Chem. Pharm. Bull, 24, 1114-1115 https://doi.org/10.1248/cpb.24.1114
  6. Jung, J.Y., Hur, S.S. and Choi, Y.H. (1999) Studies on the efficient extraction process of alginic acid in sea tangle. Food Eng. Proc., 3, 90-97
  7. Kim, S.B., Park, Y.H., Hayase, F. and Kata, H. (1986) Desmutagenic effects of mailard reaction products against mutagenic heterocyclic amines. Bull Korean Fish Soc., 19, 127-135
  8. Kim, S.-H., Lim, S.-B., Ko, Y.-H., Oh, C.-K., Oh, M.-C. and Park C.-S. (1995) Extraction yield of Hizikia fusiforme by solvents and their antimicrobial effects. Bull Korea Fish Soc., 27, 462-468
  9. Lehrer, R.I., Rosenman, M., Harwig, S.S., Jackson, R. and Eisenhauer, P. (1991) Ultrasensitive assays for endogenous antimicrobial polypeptides. J. Immunol. Methods, 137, 167-173 https://doi.org/10.1016/0022-1759(91)90021-7
  10. Noda, H., Amano, H., Arshima, S., Hashimoto, S. and Nisizama, K. (1989) Studies on the antitumor activity of marine algae. Bull Japan Soc. Sci. Fish, 55, 1259-1264 https://doi.org/10.2331/suisan.55.1259
  11. Park, N.G., Yamato, Y., Lee, S.M., Sugihara, G., Park, J.-S. and Kang, S.-W. (1996). The interaction of mastoparan B from venom of hornet Vespa basalis with phospholipid matrices. Bull. Korean Chem. Soc., 17, 50-56
  12. Ryu, B.H., Choi, B.H., Kim, D.S. and Ha, M.S. (1986) Desmutagenic effects of extract obtained from seaweeds. Bull Korean Fish Soc., 19, 502-508
  13. Ryu, B.H., Kim, D.S., Cho, K.J. and Sin, D.B. (1989) Antitumor activity of seaweeds toward sarcoma-180. Kor. J. Food Sci.Technol., 21, 595-600
  14. Yoo, J.S., Cheun, B.S. and Kim N.-G. (2001) Determination of $Na^{+}$ channel blocker in seaweeds. Korean J. Environ. Biol., 19, 107-112