The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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The Effect of Swimming and Low Power Laser on the Healing of the Freund's Complete Adjuvant Induced Arthritis in Rat

수영과 저출력 레이저 치료가 Freund's Complete Adjuvant 유발 흰쥐의 관절염 치유에 미치는 영향

  • Park, Mi-Hee (Graduate School of Health Science, Catholic University of Pusan) ;
  • Kim, Jai-Young (Department of Clinical Pathology, Catholic University of Pusan) ;
  • Rho, Min-Hee (Department of Physical Therapy, Catholic University of Pusan)
  • 박미희 (부산가톨릭대학교 물리치료) ;
  • 김재영 (부산가톨릭대학교 임상병리학과) ;
  • 노민희 (부산가톨릭대학교 물리치료학과)
  • Published : 2006.06.25
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Abstract

Purpose: This study was to find that what mechanism take effects that was Adjuvant Induced Arthritis in Sprague-Dawley rat and then treated the swimming and low power laser. Methods: Adjuvant Induced Arthritis was induced 24 Sprague-Dawley rat by the subcutaneous injection of a 0.2ml Freund's Complete Adjuvant into the right hind paw and right knee joint. Second injection used of 0.05ml Freund's Complete Adjuvant by same method. Arthritic rat were divided 3 groups; arthritic swimming group, arthritic laser group and case control group. The author performed several experimental tests which were the hind paw thickness, step length, knee joint space, activity of enzyme. Results: Hind paw thickness decreased in swimming and laser group. Left step length and knee joint space increased in swimming and laser. Conclusion: Swimming and low power laser therapy on the Adjuvant Induced Arthritis in rats does effective for the rheumatic arthritis therapy by decrease of hind paw thickness, increase of opposite side step length, increase of activity of albumin and IgG and increase of knee joint space.

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