Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Delayed Response of Tumorous type of Endobronchial Tuberculosis to Antituberculosis Treatment

치료 완료 까지 지속되었다가 치료 완료 후 호전된 종양형 기관지결핵 1예

  • Kang, Ho-Suck (Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Lee, Kwang Ha (Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Park, I-Nae (Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Shim, Tae Sun (Division of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center)
  • 강호석 (울산대학교 의과대학 서울아산병원 호흡기내과) ;
  • 이광하 (울산대학교 의과대학 서울아산병원 호흡기내과) ;
  • 박이내 (울산대학교 의과대학 서울아산병원 호흡기내과) ;
  • 심태선 (울산대학교 의과대학 서울아산병원 호흡기내과)
  • Received : 2006.02.06
  • Accepted : 2006.03.14
  • Published : 2006.03.30
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Abstract

Pulmonary tuberculomas show variable responses to treatment, with some even increasing in size after treatment. To date, however, no data have been reported on the response of tumorous type of endobronchial tuberculosis (EBTB-T) to treatment observed both bronchoscopically and histologically. We report a case of bacteriologically- and biopsy-proven EBTB-T that showed delayed response to anti-tuberculosis treatment. Even after EBTB-T was treated with antituberculosis drugs for 15 months, the bronchoscopic findings and the histologic findings of chronic granulomatous inflammation with caseation necrosis still remained. However, in fourteen months after the completion of treatment, the lesioneventually disappeared without further treatment.

폐실질에 존재하는 결핵종의 경우 정해진 기간동안 치료하면 크기가 감소하지 않더라도 치료를 종료하고 다시 조직검사를 시행하지 않는 경우가 일반적이어서 치료 중 결핵종 내의 조직 소견의 변화를 평가한 보고가 국내에서는 없는 실정이다. 이에 저자들은 세균학적 및 조직학적으로 확진된 종양형 기관지결핵에서 치료 중 반복적으로 기관지내시경 검사 및 조직검사를 시행하여 치료반응을 평가한 예로, 15개월 간의 치료에도 불구하고 육안적으로 종괴가 관찰되고 조직소견상 만성육아종성염증이 지속되었으나 치료 종료 후 자연적으로 기관지내 종괴가 소멸된 환자를 경험하였기에 이를 보고하는 바이다.

Keywords

References

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