Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Goodpasture's Syndrome Combined with Crohn's Disease

크론씨 병에 동반된 Goodpasture 증후군 1예

  • Kim, Ji-Yon (Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Bae, Jun-Yong (Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Jung, Eun-Jung (Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Kim, Yang-Ki (Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Lee, Young Mok (Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Kim, Ki-Up (Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Uh, Soo-taek (Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Hwang, Jung-Hwa (Department of Radiology, Soonchunhyang University, School of Medicine) ;
  • Jin, So-Young (Department of Clinical Pathology, Soonchunhyang University, School of Medicine) ;
  • Lee, Dong-Wha (Department of Clinical Pathology, Soonchunhyang University, School of Medicine)
  • 김지연 (순천향대학교 의과대학 내과학교실) ;
  • 배준용 (순천향대학교 의과대학 내과학교실) ;
  • 정은정 (순천향대학교 의과대학 내과학교실) ;
  • 김양기 (순천향대학교 의과대학 내과학교실) ;
  • 이영목 (순천향대학교 의과대학 내과학교실) ;
  • 김기업 (순천향대학교 의과대학 내과학교실) ;
  • 어수택 (순천향대학교 의과대학 내과학교실) ;
  • 황정화 (순천향대학교 의과대학 진단방사선과교실) ;
  • 진소영 (순천향대학교 의과대학 병리학교실) ;
  • 이동화 (순천향대학교 의과대학 병리학교실)
  • Received : 2006.05.18
  • Accepted : 2006.08.14
  • Published : 2006.10.30
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Abstract

A 29-year-old male patient was admitted due to his general weakness and poor oral intake for several months. He was diagnosed as having Crohn disease 16 years ago and total colectomy was performed 10 years ago. On the 3rd day after admission, gross hematuria and sudden hemoptysis combined with diffuse infiltration were noted on chest X-ray. His symptoms and the diffusely increased lung opacities improved with administering high-dose steroid therapy. Later, anti-GBM antibody was found to be positive on the laboratory findings. We report here on a rare case of Goodpsture syndrome combined with prolonged Crohn disease along with a review of literature.

Goodpasture 증후군은 원인 불명의 병인을 가진 드문 질환으로 질병의 경과가 급속히 진행하므로 조기에 진단을 하여 조기에 치료방법을 결정하는 것이 질병의 예후와 큰 연관성을 가진다. 크론씨 병에서 혈관염에 의한 폐 합병증을 보이는 경우는 드물어 국내에는 이와 관련된 보고가 없었으며, 17년 전 항문 누공과 농양으로 크론씨 병으로 진단 받고 10년 전 전대장 절제술을 시행한 이후 추적 관찰하는 도중 발견된 Goodpasture 증후군 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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