Pathological and serological detection of bovine viral leukosis in a dairy farm in Jeonbuk province

유우농장에서 발생한 소바이러스성 백혈병의 병리학적 및 혈청학적 조사

  • Jo Young-Suk (Jeonbuk Livestock Devlopment & Research Institute) ;
  • Jang Sae-Gun (Jeonbuk Livestock Devlopment & Research Institute) ;
  • Chu Keum-Suk (Jeonbuk Livestock Devlopment & Research Institute) ;
  • Choi Eun-Young (Jeonbuk Livestock Devlopment & Research Institute) ;
  • Chon Hee-Woong (Jeonbuk Livestock Devlopment & Research Institute) ;
  • Hong Jae-Hee (Bio-Safety Research Institute, Chonbuk National University) ;
  • Lim Chae-Woong (Bio-Safety Research Institute, Chonbuk National University)
  • 조영숙 (전라북도 축산진흥연구소 익산지소) ;
  • 장세군 (전라북도 축산진흥연구소 익산지소) ;
  • 추금숙 (전라북도 축산진흥연구소 익산지소) ;
  • 최은영 (전라북도 축산진흥연구소 익산지소) ;
  • 천희웅 (전라북도 축산진흥연구소 익산지소) ;
  • 홍재희 (전북대학교 생체안전성연구소) ;
  • 임채웅 (전북대학교 생체안전성연구소)
  • Published : 2006.06.01

Abstract

Bovine viral leukosis is a viral disease of cattle characterized by the development of tumors in the lymphatic tissue. A female Holstein, 3-year-old, was submitted for diagnosis at the Diagnostic laboratory, Chonbuk National University. Clinical sign of the affected animal showed emaciation, enlargement of superficial lymph node and mild diarrhea. Remarkable lesions were enlargement of many internal lymph nodes. Histopathology revealed excessive neoplastic lymphoid cells characteristic of BVL infection. Subsequently, serums from all cattle were collected and serological examination was done where a 85% seropositive rate was detected using ELISA test. ELISA method showed a comparatively 75% higher detection rate than the agar gel immunodiffusion (AGID) test (85% vs 40%). Serologically positive cattle were variably detected in all ages from under 1 year to over 6 year of age. Hematological examination consistently showed leukocytosis and a differential lymphocytosis of seropositive cattle. Detailed comparative pathological and serological data diagnosed the presence of bovine viral leukosis.

Keywords

References

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