Biomedical Science Letters (대한의생명과학회지)
- Volume 12 Issue 2
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- Pages.119-125
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- 2006
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
Effects of Mechanical Stimuli on the Cell Proliferation and Collagen Production on the Micropatterned Substrate
- Park Su-A (Department of Biomedical Engineering, Inje University) ;
- Kim In-Ae (Department of Biomedical Engineering, Inje University) ;
- Kim Chong-Rak (Department of Biomedical Laboratory Science, Inje University) ;
- Shin Ji-Won (Department of Biomedical Engineering, Inje University) ;
- Heo Su-Jin (Department of Biomedical Engineering, Inje University) ;
- Hwang Young-Mi (Department of Biomedical Engineering, Inje University) ;
- Kim Dong-Hwa (Department of Biomedical Engineering, Inje University) ;
- Shin Jung-Woog (Department of Biomedical Engineering, Inje University)
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- 신정욱 (인제대학교 의용공학과)
- Published : 2006.06.01
Abstract
In relation to the tissue engineering, the cellular responses to the morphology of the scaffold surface are interesting topics. Human ligament fibroblasts (HLFs) were cultured on the micrpatterned silicone substrates subjected to cyclic stretch to simulate ligament motion. Groove and ridge width of silicone substrates was 10/50, 20/50, 20/10, and 20/20
Keywords
- Biomechanical condition;
- Human ligament fibroblasts (HLFs);
- Micropatterned silicone;
- Cell proliferation;
- Collagen production