Journal of Haehwa Medicine (혜화의학회지)
- Volume 15 Issue 2
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- Pages.135-148
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- 2006
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- 2586-3002(pISSN)
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- 2586-3347(eISSN)
Effects of Sophorae Radix (SFR) on Allergic Inflammation related Atopy Dermatitis
고삼(苦蔘)이 알러지성 염증 반응에 미치는 영향
- Yu, Mao-Lun (Department of internal Medicin,, College of Oriental Medicine, Daejeon University) ;
- Koo, Young-Sun (Department of internal Medicin,, College of Oriental Medicine, Daejeon University) ;
- Kim, Dong-Hee (Department of Pathology, College of Oriental Medicine, Daejeon University)
- Accepted : 2006.12.15
- Published : 2006.12.31
Abstract
Sophorae Radix (SFR) is known as a therapeutic drug that has been used in Oriental traditional medicine for the treatment of skin and mucosal ulcers, gastrointestinal hemorrhage, diarrhea, inflammation and arrhythmia. In the present study, we examined the effects of the aqueous extract of SFR on anti-inflammation, anti-allergic and anti-oxidant effect in various cell lines; they include mouse lung fibroblast cells (hFCs), human mast cells (HMC-1), human monocytic cells (THP-1), and RAW 264.7 cells. Treatment with SFR extract at a concentration of 250
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