Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Reversible Brain Dysfunction in MELAS Syndrome

가역적인 뇌기능장애를 보인 MELAS 증후군

  • Chung, Jin-Seong (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
  • Lee, Hak-Seung (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
  • Park, Hyun-Young (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
  • Chang, Hyuk (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
  • Kim, Yo-Sik (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science) ;
  • Cho, Kwang-Ho (Department of Neurology, Wonkwang University School of Medicine, Institue of Wonkwang Medical Science)
  • 정진성 (원광대학교 신경과학교실, 원광의과학 연구소) ;
  • 이학승 (원광대학교 신경과학교실, 원광의과학 연구소) ;
  • 박현영 (원광대학교 신경과학교실, 원광의과학 연구소) ;
  • 장혁 (원광대학교 신경과학교실, 원광의과학 연구소) ;
  • 김요식 (원광대학교 신경과학교실, 원광의과학 연구소) ;
  • 조광호 (원광대학교 신경과학교실, 원광의과학 연구소)
  • Published : 2006.06.30
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Abstract

The MELAS (Mitochondrial Encephalomyopathy with Lactic Acidosis, and Stroke-like episodes) syndrome is one of the inherited mitochondrial disorder. We have experienced a 16-year-old girl with headaches and left hemianopsia. Diagnosis of MELAS syndrome with multiple brain parenchymal lesions was confirmed by gene study. The stroke-like lesion of MELAS syndrome showed significant improvement in radiological follow up study. Therefore, MRI findings in MELAS could be interpreted as metabolic cellular dysfunction rather than ischemic vasculopathy.

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