Proteomes Induced by S-Adenosyl-L-Methionine in Streptomyces coelicolor A3(2)

  • Kim Kwang-Pyo (Bio/Molecular Informatics Center, Konkuk University) ;
  • Shin Choon-Shik (Bio/Molecular Informatics Center, Konkuk University) ;
  • Lee Soo-Jae (School of Chemistry and Molecular Engineering, Seoul National University) ;
  • Kim Ji-Hye (Bio/Molecular Informatics Center, Konkuk University) ;
  • Young Jung-Mo (Bio/Molecular Informatics Center, Konkuk University) ;
  • Lee Yu-Kyung (Bio/Molecular Informatics Center, Konkuk University) ;
  • Ahn Joong-Hoon (Bio/Molecular Informatics Center, Konkuk University) ;
  • Suh Joo-Won (Institute of Bioscience and Biotechnology and Department of Biological Science, Myongji University) ;
  • Lim Yoong-Ho (Bio/Molecular Informatics Center, Konkuk University)
  • 발행 : 2006.05.01

초록

It was reported that an accumulation of Sadenosyl-L-methionine increases production of actinorhodin in Streptomyces lividans and induces antibiotic biosynthetic genes. We also obtained the same result in Streptomyces coelicolor A3(2). Therefore, in order to identify proteins changed by the addition of S-adenosyl-L-methionine in S. coelicolor A3(2), LC/MS/MS analyses were carried out. Thirteen proteins that were not observed in the control were found.

키워드

참고문헌

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