Environmental Analysis Health and Toxicology

환경독성보건학회 (The Korean Society of Environmental Health and Toxicology)
권호 표지

혈중 납 농도와 역학적 요인 및 체내 철 수준과의 관련성

The Relation between Blood Lead Concentration, Epidemiologyic Factors and Body Iron Status

  • 박상우 (중앙대학교 의과대학 예방의학교실) ;
  • 김기영 (중앙대학교 의과대학 예방의학교실) ;
  • 김동원 (중앙대학교 의과대학 예방의학교실) ;
  • 최성진 (중앙대학교 의과대학 예방의학교실) ;
  • 김현숙 (중앙대학교 의과대학 예방의학교실) ;
  • 최병선 (중앙대학교 의과대학 예방의학교실) ;
  • 최미경 (청운대학교 식품영양학과) ;
  • 박정덕 (중앙대학교 의과대학 예방의학교실)
  • Park Sang-Woo (Department of preventive Medicine, College of Medicine, Chung-Ang University) ;
  • Kim Ki-Young (Department of preventive Medicine, College of Medicine, Chung-Ang University) ;
  • Kim Dong-Won (Department of preventive Medicine, College of Medicine, Chung-Ang University) ;
  • Choi Seong-Jin (Department of preventive Medicine, College of Medicine, Chung-Ang University) ;
  • Kim Hyun-Sook (Department of preventive Medicine, College of Medicine, Chung-Ang University) ;
  • Choi Byung-Sun (Department of preventive Medicine, College of Medicine, Chung-Ang University) ;
  • Choi Mi-Kyeong (Department of Human Nutrition & Food Science, Chungwoon University) ;
  • Park Jung-Duck (Department of preventive Medicine, College of Medicine, Chung-Ang University)
  • 발행 : 2006.06.01
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초록

Essential metals have been known to interact with non-essential toxic metals in the aspects of absorption, transport and deposition in the body. Iron deficiency has been reported to increase lead and/or cadmium absorption. The relation between iron and lead has been understood well in children but not in adults. Two hundred seventy adults (118 males and 152 females) were recruited from 3 different residental areas (rural, coastal and urban) to investigate the effects of environmental lead exposure on body iron status. The subjects were interviewed for life-style and diet of the last 24 hours, and measured for blood lead and body iron. The lead concentration in the whole blood was determined by a flameless method using an atomic absorption spectrophotometry. The body iron was evaluated with values of hemoglobin, hematocrit, RBCs, serum total iron, unsaturated iron binding capacity, total iron binding capacity and ferritin. The mean concentration of blood lead in adult was $3.31{\mu}g/dL$. The concentration was higher in male ($3.97{\mu}g/dL$) than in female ($2.86{\mu}g/dL$). The blood lead was influenced by residental area, life-style, smoking and drinking, occupation and diet habit of subjects, but not by age. A positive correlation was observed between the blood lead level and the serum iron or ferritin. These results suggest that environmental lead exposure in Korean adult may not be higher than other developed and developing countries. It is further indicated that blood lead in adult could be influenced by life-style, and environmental and genetic factors but no inverse relation with body iron as shown in children.

키워드

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