약학회지 (YAKHAK HOEJI)

  • 제50권6호
  • /
  • Pages.381-385
  • /
  • 2006
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  • 0377-9556(pISSN)
  • /
  • 2383-9457(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

정상 식이 수컷 흰쥐에서 흑삼이 체중 및 지질에 미치는 영향

Effect of Black Ginseng on Body Weight and Lipid Profiles in Male Rats Fed Normal Diets

  • 송규용 (충남대학교 약학대학) ;
  • 오한진 (성균관대학교 의과대학) ;
  • 노성수 (대전대학교 한의과대학 병리학교실) ;
  • 서영배 (대전대학교 한의과대학 병리학교실) ;
  • 박용진 (백남한의원) ;
  • 명창선 (충남대학교 약학대학)
  • Song, Gyu-Yong (College of Pharmacy, Chungnam National University) ;
  • Oh, Han-Jin (Cheil General Hospital & Women's Health Care Center, Sungkyunkwan University School of Medicine) ;
  • Roh, Seong-Soo (Department of Pathology, College of Oriental Medicine, Daejeon University) ;
  • Seo, Young-Bae (Department of Pathology, College of Oriental Medicine, Daejeon University) ;
  • Park, Yong-Jin (Baeknam Oriental Hospital) ;
  • Myung, Chang-Seon (College of Pharmacy, Chungnam National University)
  • 발행 : 2006.12.31
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초록

Previously we have reported that black ginseng was produced by nine-time repeated steaming 5-year fresh ginsengs at 95${\circ}$C for 3hr in pottery apparatus and drying at 60${\circ}$C for 12${\sim}$36 hr and had an outstanding anticancer activity. This study was designed to examine the ability of black ginseng to suppress body weight gain appetite, and to investigate the effect of black ginseng on lipid profile in male rats fed normal diets. The extract of black ginseng was administered daily for 3 weeks, and the changes of body weight and food intake were measured. After administering the extracts for 3 weeks, the fat weight and serum lipid levels were also measured. Black ginseng persistently suppressed weigh gain and food intake was also reduced, but not significantly; The weight of both epididymal and abdominal fats was decreased In black ginseng-treated rats. Serum triglyceride level in rats administered with black ginseng was also significantly lowered. Therefore, these results reveal that the repeated administration of black ginseng causes a suppression of body weigh gain by decreasing triglyceride level in blood and body fat deposit.

키워드

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