References
- Olukoga, A. and Donaldson, D. : Liquorice and its health implications. J. R. Soc. Health 120, 83 (2000) https://doi.org/10.1177/146642400012000203
- Sticher, O. : In Haensel, R., Sticher, O. and Steinegger, E. (Eds), Pharmakognosi-Phytopharmazie, 6th ed, Springer, Berlin, p. 542 (1999)
- Ohuchi, K., Kamada, Y., Levine, L. and Tsurufuji, S. : Glycyrrhizin inhibits prostaglandin E2 production by activated peritoneal macrophages from rats. Prostaglandins Med. 7, 457 (1981) https://doi.org/10.1016/0161-4630(81)90033-1
- Junei, K., Tomoki, H., Ryota, T., Tsuneatsu, N., Masafumi, O., Toshihiro N. and Hikaru, O. : Hepatoprotective constituents in plants 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells. Biol. Pharm. Bull. 26, 1357 (2003) https://doi.org/10.1248/bpb.26.1357
- Yoshikawa, M., Toyohara, M., Usda, S., Shiroi, A., Takeuchi, H., Nishiyama, T., Yamda, T., Fukui, H. and Ishizaka, S : Glycyrrhizin inhibits TNF-induced, but not Fas-mediated, apoptosis in the human hepatoblastoma lin HepG2. Biol. Pharm. Bull. 22, 951 (1999) https://doi.org/10.1248/bpb.22.951
- Kiso, Y., Tohkin, M., Hikino, H., Hattori, M., Sakamoto, T. and Namba, T. : Mechanism of antihepatotoxic activity of glycyrrhizin. I: Effect on free radical generation and lipid peroxidation. Planta Med. 50, 298 (1984) https://doi.org/10.1055/s-2007-969714
- Takino, T. : The effects of hepatotherapeutic drugs on chronic liver disease evaluated by double blind trials in Japan. J. Kyoto Perfect Univ. Med. 93, 689 (1984)
- Zhang, D. Y., Wu, J., Ye, F., Xue, L., Jiang, S., Yi, J., Zhang, W., Wei, H., Sung, M., Wang, W. and Li, X. : Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. Cancer Res. 14, 4037 (2003)
- Motoo, Y. and Sawabu, N. : Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines. Cancer Lett. 1, 91 (1994) https://doi.org/10.1016/S0304-3835(75)95563-9
- Fukutake, M., Yokota,S., Kawamura, H., Iizuka, A., Amagaya, S., Fukuda, K. and Komatsu, Y. : Inhibitory effect of Coptidis Rhizoma and Scutellariae Radix on azoxymethane-induced aberrant crypt foci formation in rat colon. Biol. Pharm. Bull. 8, 814 (1998)
- Chou, T. C., Chang, L. P., Li, C. Y., Wong, C. S. and Yang, S. P. : The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Anesth. Analg. 6, 1724 (2003)
- Krakauer, T., Li, B. Q. and Young, H. A. : The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. FEBS Lett. 500, 52 (2001) https://doi.org/10.1016/S0014-5793(01)02584-4
- Lin, C. C. and Shieh, D. E. : The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin. Am. J. Chin. Med. 1, 31 (1996)
- Hwang, J. M., Wang, C. J., Chou, F. P., Tseng, T. H., Hsieh, Y. S., Hsu, J. D. and Chu, C. Y. : Protective effect of baicalin on tert-butyl hydroperoxide-induced rat hepatotoxicity. Arch. Toxicol. 79, 102 (2005) https://doi.org/10.1007/s00204-004-0588-6
-
Mujumdar, A. M., Upadhye, A. S. and Pradhan, A. M. : Effect of Azadirachta indica leaf extract on
$CCl_{4}$ induced hepatic damage in albino rats. Indian Journal of Pharmaceutical Science 60, 363 (1998) - Esterbauer, H., Zollner, H. and Schur, R. J. : Hydroxyalkenals; cytotoxic products of lipidperoxidation. Science Biochem. 1, 311 (1988)
- Vaca, C. E., Vodicka, P. and Hemminki, K. : Determination of malonaldehyde-modified 2'-deoxyguanosine-3'-monophosphate and DNA by 32P-postlabelling. Carcinogenesis 13, 593 (1992) https://doi.org/10.1093/carcin/13.4.593
- Decker, K. and Keppler, D. : Galactosamine-induced liver injury. In Popper, H. and Schaffiner, F. (Eds.), Progress in Liver Disease, Grune, Stratton, New York, p. 183 (1972)
- Konishi, Y., Shinozuka, H. and Farber, J. L. : The inhibition of rat liver nuclear ribonucleic acid synthesis by galactosamine and its reversal by uridine. Lab. Invest. 30, 751 (1974)
-
Shim, S. B., Kim, N. J. and Kim, D. H. :
${\beta}$ -Glucosidase inhibitory activity and hepatoprotective effect of$18{\beta}$ - glycyrrhetinic acid from the rhizomes of Glycyrrhiza uralensis. Planta Med. 66, 40 (2000) https://doi.org/10.1055/s-2000-11109 - Berry, M. N. andFriend, D. S. : High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. J. Cell Biol. 43, 506 (1969) https://doi.org/10.1083/jcb.43.3.506
- Kleinman, H. K., McGoodwin, E. B., Rennard, S. I. and Martin, G. R. : Preparation of collagen substrates for cell attachment: effect of collagen concentration and phosphate buffer. Anal. Biochem. 94, 308 (1979) https://doi.org/10.1016/0003-2697(79)90365-8
- Kiso, Y., Tohkin, M. and Hikino, H. : Assay method for antihepatotoxic activity using carbon tetrachloride induced cytotoxicity in primary cultured hepatocytes. Planta Med. 49, 222 (1983) https://doi.org/10.1055/s-2007-969855
- Tseng, T. H., Wang, C. J., Kao, E. S. and Chu, H. Y. : Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes. Chem. Biol. Interact. 101, 137 (1996) https://doi.org/10.1016/0009-2797(96)03721-0
- Kiso, Y., Tohkin, M. and Hikino, H. : Assay method for antihepatotoxic activity using galactosamine-induced cytotoxicity in primary-cultured hepatocytes. J. Nat. Prod. 46, 841 (1983) https://doi.org/10.1021/np50030a003
- Clawson, G. A. : Mechanism of carbon tetrachloride hepatotoxicity. Pathol. Immunopathol. Res. 8, 104 (1989) https://doi.org/10.1159/000157141
- Rush, G. F., Gorski, J. R., Ripple, M. G., Sowinski, J., Bugelski, P. and Hewitt, W. R. : Organic hydroperoxide-induced lipid peroxidation and cell death in isolated hepatocytes. Toxicol. Appl. Pharmacol. 78, 473 (1985) https://doi.org/10.1016/0041-008X(85)90255-8
- Taniguchi, H., Yomota, E., Nogi, K. and Onoda, Y. : Effects of anti-ulcer agents on ethanol-induced gastric mucosal lesions in D-galactosamine-induced hepatitis rats. Arzneimittelforschung 52, 600 (2002)