Korean Journal of Plant Resources (한국자원식물학회지)

The Plant Resources Society of Korea (한국자원식물학회)
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Effect of Mahwang (Ephedrae herba) extract on serum Biological Values and Blood cell Composition

마황추출액이 혈액의 생물학적 수치 및 혈구 구성에 미치는 영향

  • Park Young-Hoon (Dept. of Fine Chemistry and Material Science, College of science and Engineering, Sang-ji University)
  • 박영훈 (상지대학교 이공과대학 정밀화학신소재학과)
  • Published : 2006.04.01
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Abstract

Effects of mahwang(Ephedrae herba) extract on plasma lipid composition, GOT, GPT activity and blood cell composition were investigated in rats. Concentrations of FFA was not significantly different in all treatment groups. Concentrations of triglyceride and total cholesterol in plasma were decreased in mahwang(Ephedrae herba) extract groups. However concentrations of HDL-cholesterol and LDL-cholesterol showed no significant difference in all treatment groups. GOT activities were increased in mahwang(Ephedrae herba) extract 300mg/kg group. However the values of GPT showed no significant difference in all treatment groups. Counts of RBC were increased in mahwang(Ephedrae herba) extract 300mg/kg group. Counts of WBC showed no significant difference in all treatment groups. In WBC composition, neutrophils were increased, but other cells were not affected by mahwang extract treatment.

마황 추출액이 흰쥐의 혈액내 지질구성, 간장기능 및 혈구성상에 미치는 영향을 검토했다. 혈장내 FFA 농도는 처리군 간에 유의한 차이를 나타내지 않았다. 그러나 triglyceride 농도는 마황 첨가량이 증가함에 따라 감소하였다. 총콜레스테롤량은 마황 첨가군에서 현저하게 감소했다. 그러나 HDL 및 LDC-cholesterol 농도는 처리군 간에 유의한 차이를 나타내지 않았다. GOT 활성치는 마황 첨가군에서 높은 경향을 보였으나, GPT 활성치는 처리군 간에 유의한 차이를 나타내지 않았다. RBC는 마황 첨가군에서 높은 수치를 보였으나, Hb 및 PCV는 처리군 간에 유의한 차이를 보이지 않았다. WBC 총수는 처리군 간에 유의한 차이를 나타내지 않았다. 백혈구 구성비는 neutrophils의 비율이 마황 첨가군에서 증가하는 경향을 보였으나 나머지 종류들은 처리군 간에 유의한 차이를 나타내지 않았다.

Keywords

References

  1. Ahrens, E, H., W. J. Insull, R. Blomstrand, J. Hirsh, T. T. Tsaltas and M. I. Peterson . 1957. The influence of dietary fat on serum lipids levels in man. Lancet 1: 943-954
  2. Bidlack, W. R. and A. L. Tappel. 1973. Damage to microsomal membrane by lipid peroxidation. Lipids 8: 177-178 https://doi.org/10.1007/BF02544631
  3. Choi, M. Y., E. J. Choi, E. Lee, T. J. Rhim, B. C. Cha and H. J. Park. 1997. Antimicrobial activities of pine needle (Pinus densiflora seib et Zucc.). Kor J. Appl Microbiol Biotechnol 25: 293-297
  4. Kang, Y. H., Y. K. Park, T. Y. Ha and K. D. Moon. 1996. Effects of pine needle extracts on enzyme activities of serum and liver, liver morphology in rats fed high fat diet. J. Korean Soc Food Nutr 25: 374-378
  5. Kim, S. H. and M. J. Jo. 1972. A study of metabolic effect in high and low fat diet on albino rat. J. Nutr 5: 169-183
  6. Kim, W. Y. and H. S. Park. 1981. The effect of dietary fat levels and protein source in early life on the cholesterol and lipid metabolism in adult rats. Korean J. Nutr 14: 136-147
  7. Linder, M. C. 1991. Nutrition and merabolism of fats. In : Linder MC ed. Nutritional Biochemistry and Metabolism with Clinical Applications, 2nd ed. Elsevier, New York, Amsterdam, Oxford: 79-83
  8. Liber, C. S. 1994. Alcohol and the Liver : 1994 update. Gastero enteroligy 106 : 1085-1105 https://doi.org/10.1016/0016-5085(94)90772-2
  9. Saito, M. 1988. Interaction between lipid peroxide formation and nutritional status. J. JPN Soc Nutr Food Sci 41: 343-349 https://doi.org/10.4327/jsnfs.41.343
  10. Sin, M. K. and G. J. Han. 1997. The effects of green tea on the serum lipid and liver tissue of cholesterol fed rats. Korean J. Sci Technol 29: 1255-1263
  11. Vergroeson, A. T. 1997. Physiological effects of dietary linoleic acid. Nutr Rev 35: 1-9
  12. Younes, M. and C. P. Siegers. 1980. Lipid peroxidation as a consequence of glutathione depletion in rat and mouse liver. Res Comm Chem Path Pharm 27: 119-129
  13. 문관심. 1994. 약초의 성분과 이용, 서울, 일월서각. 124-125
  14. 생약연구회. 1985. 개정판 현대생약학, 한국학습교재사. 292-294
  15. 여명천, 유문발. 1993. 중약적중독여방치, 중광대학출판사. 27-29
  16. 용준충, 1989. 임상중약학. 북경, 인민위생출판사. 109-110
  17. 이상인, 안덕균, 신민교. 1982. 한약임상응용, 서울, 성보사. 44-52
  18. 왕병묵, 왕령:신농본초경경고증, 길림, 길림과학기술출판사. 316-317
  19. 조강준. 1989. 중초약중독급구, 사천성, 성도전파공정학원출판사. 274-275
  20. 채인식, 1987. 상한록역전, 서울, 고문사. 298-299