Journal of Periodontal and Implant Science

  • 제36권2호
  • /
  • Pages.515-529
  • /
  • 2006
  • /
  • 2093-2278(pISSN)
  • /
  • 2093-2286(eISSN)
대한치주과학회 (Korean Academy of Periodontology)
권호 표지

하악 2급 이개부 병변에서 이종골 이식시 Fibrin adhesive와 Calcium sulfate barrier의 사용에 타른 임상적 효과에 대한 비교 연구

A comparative study of the clinical effects of Fibrin adhesive and Calcium sulfate barrier in the treatment of mandibular class II furcations using Xenograft

  • 곽승호 (단국대학교 치과대학 치주과학교실) ;
  • 정진형 (단국대학교 치과대학 치주과학교실) ;
  • 임성빈 (단국대학교 치과대학 치주과학교실) ;
  • 홍기석 (단국대학교 치과대학 치주과학교실)
  • Kwak, Seung-Ho (Department of Periodontology, College of Dentistry, Dan-Kook University) ;
  • Chung, Chin-Hyung (Department of Periodontology, College of Dentistry, Dan-Kook University) ;
  • Lim, Sung-Bin (Department of Periodontology, College of Dentistry, Dan-Kook University) ;
  • Hong, Ki-Seok (Department of Periodontology, College of Dentistry, Dan-Kook University)
  • 발행 : 2006.06.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Periodontal regeneration refers to the restoration of bone, cementum and periodontal ligament to their original levels before damage from periodontal disease process. Various surgical techniques to the promotion of periodontal regeneration have been used. Bone graft and guided tissue regeneration have used for the regeneration of furcation involvements which caused by periodontal disease. Fibrin adhesive is agents that have been shown to be effective in periodontal regeneration and biological carrier. Calcium sulfate which is one of the resorbable barrier materials has used for guided tissue regeneration. The purpose of this study was to compare the clinical effects between bone graft using fibrin adhesive and calcium sulfate barrier in the mandibular class II furcation involvement. For the study, twenty-six class II furcation involved teeth were surgically treated. 13 furcation defects(test group) were treated with bonegraft and fibrin adhesive and the others(control group) were treated with bone graft and calcium sulfate barrier. Pocket depth, clinical attachment level and gingival recession were measured at baseline, postoperative 3 and 6 months. The results of the study are as follows: 1. The change of pocket depth and clinical attachment level in both groups was decreased significantly at 3, 6 months than at baseline(p<0.05). 2. The change of gingival recession in both groups was increased significantly at 3, 6 months than at baseline(p<0.05). 3. The change of pocket depth and clinical attachment level in both groups was decreased at 3, 6 months, and the change of gingival recession in both groups was increased at 3, 6 months but there were no statistically or clinically significant differences with both groups. 4. The significant reduction of the pocket depth and clinical attachment level exhibited marked changes at 3 months in both groups. In conclusion, the results of this study suggest that there are no statistically or clinically significant differences between fibrin adhesive and calcium sulfate barrier in the treatment of class II furcations using xenograft.

키워드

참고문헌

  1. Ash, M.M., Gitlin, B.N. and Smith, W.A. : Correlation between plaque and gingivitis. J Periodontol 1964;35:424-429 https://doi.org/10.1902/jop.1964.35.5.424
  2. Newell, D.H. : Current Status of the management of teeth with furcation invasions. J Periodontol 1981;52:559-564 https://doi.org/10.1902/jop.1981.52.9.559
  3. Socransky, S.S. : Relationship of bacteria to the etiology of periodontal disease. J Dent Res 1970;49:203-211 https://doi.org/10.1177/00220345700490020401
  4. Waerhaug, J. : A method for evaluation of periodontal problems on extracted teeth. J Clin Periodontol 1975;2:160-175 https://doi.org/10.1111/j.1600-051X.1975.tb01738.x
  5. Everett, F.G., Jump, E.B., Holder, T.D. and Williams, G.C. : The intermediate bifurcational ridge. A study of the morphology of the bifurcation of the lower first molar. J Dent Res 1958;37: 162-175 https://doi.org/10.1177/00220345580370011001
  6. Grewe, J.M., Meskin, L.H. and Miller, T. : Cervical enamel projections: prevalence, location and extent with associated periodontal implications. J Periodontol 1965;36: 460-475 https://doi.org/10.1902/jop.1965.36.6.460
  7. Larato, D.C. : Some anatomical factors related to furcation involvement. J Periodontol 1975;46:608-615 https://doi.org/10.1902/jop.1975.46.10.608
  8. Masters, D.H. and Hoskins, S.W. : Projection of cervical enamel into molar furcations. J Periodontol 1963;35:49-65
  9. Swan, R.H. and Hurt, W.C. : Cervical enamel projections as an etiologic factor in furcation involvement. J Am Dent Assoc 1976;93:342-355 https://doi.org/10.14219/jada.archive.1976.0527
  10. Brunsvold M, Mellonig j : Bone graft and periodontal regeneration. Periodontol 2000 1993;1:80-91 https://doi.org/10.1111/j.1600-0757.1993.tb00209.x
  11. Hiatt R, Schallhorn R : Intraoral transplants of cancellous bone and marrow in periodontal lesions. J Periodontol 1973:44: 194-208 https://doi.org/10.1902/jop.1973.44.4.194
  12. Schwartz Z, Somers A, Mollonig JT et al. : Ability of commercial demineralized freeze-drived bone allograft to induce new bone formation is dependent on donor age but not gender. J Periodotol 1998;69: 470-478 https://doi.org/10.1902/jop.1998.69.4.470
  13. Becker W, Urist MR, Tucker LM, Becker BE, Ochsenbein C : Human demineralized freeze-dried bone: Inadequate induced bone formation in athymic mice. A preliminary report. J Periodontol 1995;66:822-828 https://doi.org/10.1902/jop.1995.66.9.822
  14. Wetzel AC, Stich H, Caffesse RG : Bone apposition onto oral implants in the sinus area filled with different grafting materials. A histological study in the beagle dogs. Clinical Oral Implants Research 1995;6:155-163 https://doi.org/10.1034/j.1600-0501.1995.060304.x
  15. Melcher AH. : On the repair potential of periodontal tissue. J Periodontol 1976;47: 256-260 https://doi.org/10.1902/jop.1976.47.5.256
  16. Gottlow J, Nyman S, Lindhe J, Karring T, Wennstrom J. : New attachment formation in the human periodontium by guided tissue regeneration. Case reports. J Clin Periodontol 1986;13:604-616 https://doi.org/10.1111/j.1600-051X.1986.tb00854.x
  17. Nyman S, Lindhe J, Karring T, Rylander H. : New attachment following surgical treatment of human periodontal disease. J Clin Periodontol 1982;9:290-296 https://doi.org/10.1111/j.1600-051X.1982.tb02095.x
  18. Nyman S, Gottlow J, Lindhe J, Karring T, Wennstrom J : New attachment formation by guided tissue regeneration. J Periodont Res 1987;22:252-254 https://doi.org/10.1111/j.1600-0765.1987.tb01581.x
  19. Becker W, Becker B, Berg L, Prichard J, Caffesse R, Resenberg E : New attachment after treatment with root isolation and vertical osseous defects. Int J Periondontics Restorative Dent 1988;8:8-23
  20. Martas H. : Fibrin seal: the state of the art. J Oral Maxillofac Surg. 1985;43: 605-611 https://doi.org/10.1016/0278-2391(85)90129-6
  21. Bosch P, Lintner F, Arbes H, Brand G. : Experimental investigations of the effects of the fibrin adhesive on the Kiel heterologous bone graft. Arch Orthop Trauma Surg. 1980;96:177-185 https://doi.org/10.1007/BF00457781
  22. 김영운, 류선열 : 성견의 골결손부에서 3종의 지혈제가 골재생에 미치는 영향. 전남치대 논문집 1994;6:279-293
  23. Frame JW, Rout PG, Browne RM. : Ridge augmentation using solid and porous hydroxyapatite particles with and without autogenous bone or plaster. J Oral Maxillofac Surg 1987;45:771-777 https://doi.org/10.1016/0278-2391(87)90200-X
  24. Sottosanti JS. : Calcium sulfate: a biodegradable and biocompatible barrier for guided tissue regeneration. Compend Cantin Educ Dent 1992;13:226-234
  25. Sottosanti JS. : Aesthetic extraction with calcium sulfate and the principles of guided tissue regeneration. Pract Periodont & Aesthetic Dent 1993;5:61-69
  26. Sottosanti JS. Calcium sulfate is a safe, resorbable barrier adjunct to implant surgical procedures. Dental Implnatology Update 1993;4:69-73
  27. Bier SJ. : Plaster of Paris, an surgical dressing. New York State Dent J 1970; 36:347-352
  28. Bahn SL. : Plaster: a bone substitute. Oral Surg Oral Med Oral Pathol 1966;21:672-681 https://doi.org/10.1016/0030-4220(66)90045-4
  29. Radentz WH, Collings CK. : The implantation of plaster of Paris in the alveolar process of the dog. J Periodontol 1965;36:357-364 https://doi.org/10.1902/jop.1965.36.5.357
  30. 최동훈, 최성호, 조규성, 채중규, 김종관, 문익상. : The effect of calcium sulfate on the periodontal healing of 2-wall intrabony defects in dogs. 대한치주과학회지 1997;27:395-403
  31. Kim CK, Chai JK, Cho KS, Moon IS, Choi SH, Sottosanti JS, Wikesjo ME. : Periodontal repair in intrabony defects treated with a calcium sulfate implant and calcium sulfate barrier. J Periodontol 1998;69:1317-1324 https://doi.org/10.1902/jop.1998.69.12.1317
  32. Bell WH. : Resorption characteristics of bone substitutes. Oral Surg Oral Med Oral Pathol 1964;17:650-657 https://doi.org/10.1016/0030-4220(64)90372-X
  33. Glickman I. : Bifurcation involvement in periodontal disease. J Am Dent Assoc 1950;40:528 https://doi.org/10.14219/jada.archive.1950.0087
  34. Oison, A.M. : The root surface and regulation ; present therapeutic limitations and future biologic potentials. J Clin Periodontol 1986;13: 995-1001 https://doi.org/10.1111/j.1600-051X.1986.tb01439.x
  35. Rober. C.B. : Furcation development of human mandibular first molar teeth. A histologic graphic reconstructional study. J Periodontal Res 1983;18:412-419 https://doi.org/10.1111/j.1600-0765.1983.tb00377.x
  36. Sandier, H.C., and Stahal, S.S. : The measurement of periodontal disease prevalence. JADA 1959;58:93-111
  37. Pontoriero R, Lindhe J, Nyman S, Karring T, Rosenberg E, Sanavi F : Guided tissue regeneration in degree II furcation-involved mandibular molars. A clinical study. J Clin Periodontol 1988;15:247-254 https://doi.org/10.1111/j.1600-051X.1988.tb01578.x
  38. Lekovic V, Kenney EB, Kovacevic K, Carranza Jr FA : Evaluation of guided tissue regeneration in class II furcation defects A clinical re-entry study. J Periodontol 1989;60:694-698 https://doi.org/10.1902/jop.1989.60.12.694
  39. Caffesse R, Smith BA, Duff B, Morrison EC, Merrill D, Becker W : Class II furcations treated by guided tissue regeneration in humans. Case reports. J Periodontol 1990;61:510-514 https://doi.org/10.1902/jop.1990.61.8.510
  40. Araujo MG, Berglundh T, Lindhe J. : GTR treatment of degree III furcation defects with 2 different resorbable barriers An experimental study in dogs. J Clin Periodontol. 1998;25(3):253-259 https://doi.org/10.1111/j.1600-051X.1998.tb02436.x
  41. de Sanctis M, Zucchelli G, Clauser C. : Bacterial colonization of bioabsorbable barrier material and periodontal regeneration. J Periodontol 1996;67:1193-1200 https://doi.org/10.1902/jop.1996.67.11.1193
  42. Camargo PM, Lekovic V, Weinlaender M, Klokkevold PR, Kenney EB, Dimitrijevic B, Nedic M, Jancovic S, Orsini M. : Influence of bioactive glass on changes in alveolar process dimensions after exodontia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;90:581-586 https://doi.org/10.1067/moe.2000.110035
  43. Najjar TA, Lerdrit W, Parsons JR. : Enhanced osseointegration of hydroxyapatite implant material. Oral Surg Oral Med Oral Pathol 1991;71:9-15 https://doi.org/10.1016/0030-4220(91)90512-B
  44. Oklund SA, Prolo DJ, Gutierrez RV, King SE : Quantitative comparison of healing in cranial fresh autograft, frozen autografts and processed autograft, and allografts in canine skull defects. Clin Orthop 1986;205:269-291
  45. Mellonig JT, Bowers GM, Bailey RC : Comparison of bone graft materials. Part I. New bone formation with autografts and allografts determined by Strontium-85. J Periodontol 1981;52:291-296 https://doi.org/10.1902/jop.1981.52.6.291
  46. Clergeau LP, Danan M, Clergeau-Guerithault S, Brion M : Healing response to anorganic bone implantation in periodontal intrabony defects in dogs. Part I. Bone regeneration. A microradiographic study. J Periodontol. 1996;67:140-149 https://doi.org/10.1902/jop.1996.67.2.140
  47. Bowers GM, Chadorff B, Carnevale R, Mellonig JT, Corio R, Emerson J, Stevens J, Romberg E : Histologic evaluation of new attachment apparatus formation in humans. Part I. J Periodontol 1989;60:664-674 https://doi.org/10.1902/jop.1989.60.12.664
  48. Bowers GM, Chadorff B, Carnevale R, Mellonig JT, Corio R, Emerson J, Stevens J, Romberg E : Histologic evaluation of new attachment apparatus formation in humans. Part II. J Periodontol 1989;60:675-682 https://doi.org/10.1902/jop.1989.60.12.675
  49. Simonpietri JJ, Novaes AB, Batista EL, Feres EJ : Guided tissue regeneration associated with bovine-derived anorganic bone in mandibular class II furcation defects. 6-month results at re-entry J Periondontol 2000;71:904-911 https://doi.org/10.1902/jop.2000.71.6.904
  50. D. De Leonardis, A.K. Carg, V. Pedrazzoli, and G.E. Pecora : Clinical evaluation of the treatment of class II furcation involvements with bioabsorbable barriers alone or associated with demineralized freeze-deried bone allograft. J Periodontol 1999: 70: 8-12 https://doi.org/10.1902/jop.1999.70.1.8
  51. Thom JJ, Srensen H, Weis-Fogh U, Andersen M : Autologous fibrin glue with growth factors in reconstructive maxillofacial surgery. Int J Oral Maxillofac Surg 2004;33:95-100 https://doi.org/10.1054/ijom.2003.0461
  52. Grinnel F, Feld MK : Initial adhesion of human fibroblasts in serum-free medium. Possible role of secreted fibronectin. Cell 1979;17:117-129 https://doi.org/10.1016/0092-8674(79)90300-3
  53. Caffesse RG, Kerry GJ, Chaves ES : Clinical evaluation of the use of citric acid and autologous fibronectin in periodontal surgery. J Periodontol 1988;59:565-568 https://doi.org/10.1902/jop.1988.59.9.565
  54. Caffesse RG, Nasjleti CE, Anderson GB, Lopatin DE, Smith BA, Morison EC : Periodontal healing following guided tissue regeneration with citric acid and fibronectin application. J Periodontol 1991;62:21-29 https://doi.org/10.1902/jop.1991.62.1.21
  55. Pini Prato GP, De Paoli S, Clauser C : On the use of a biologic sealing system(Tissucol) in periodontal surgery. Int J Periodontics Restorative Dent 1983;33:33-38
  56. Pini Prato GP, Cortellini P, Clauser C : Fibrin and fibronectin sealing system in a guided tissue regeneration procedure. A case report. J Periodontol 1988;59:679-683 https://doi.org/10.1902/jop.1988.59.10.679
  57. Cortellini P, De-Sanctis M, Pini Prato GP, Baldi C & Clauser C : Guided tissue regeneration procedure using a fibrin-fibronectin sealing system in surgically induced recession in dogs. Int J Periodontics Restorative Dent 1991;11:151-163
  58. Hallman M, Lundgren S, Sennerby L. : Histologic analysis of clinical biopsies taken 6 months and 3 years after maxillary sinus floor augmentation with 80% bovine hydroxyapatite and 20% autogenous bone mixed with fibrin glue. Clin Implant Dent Relat Res 2001;3(2):87-96 https://doi.org/10.1111/j.1708-8208.2001.tb00236.x
  59. Dogan A, Taner L, Oygur T, Balos K. : Effects of fibrin adhesive material(Tissucol) application on furcation defects in dogs. J Nihon Univ Sch Dent 1992;34(1):34-41 https://doi.org/10.2334/josnusd1959.34.34
  60. Ohazama A, Isatsu K, Hatayama J, Okamatsu Y, Tachikawa T, Hasegawa K. : Periodontal tissue regeneration using fibrin tissue adhesive material in vitro and in vivo. Periodontal Clin Investig. 1996;18(1):26-38
  61. Cortellini P, Pini Prato GP, Tonetti MS. : No detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial. J Clin Periodontol. 1995;22(9):697-702 https://doi.org/10.1111/j.1600-051X.1995.tb00829.x
  62. Carmagnola D, Berglundh T, Lindhe J. : The effect of a fibrin glue on the integration of Bio-Oss with bone tissue. A experimental study in labrador dogs. J Clin Periodontol. 2002;29(5):377-383 https://doi.org/10.1034/j.1600-051X.2002.290501.x
  63. Reynolds MA, Bowers GM. : Fate of demineralized freeze-drived bone allografts in human intrabony defects. J Periodontol 1996;67:150-157 https://doi.org/10.1902/jop.1996.67.2.150