The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Salivary Duct Carcinoma with Mucin Containing Cells -Report of a Case Misdiagnosed as Mucoepidermoid Carcinoma on Fine Needle Aspiration Cytology-

점액세포가 관찰되는 침샘 관암종 -세침흡인 세포검사에서 점액표피모양암종으로 오인했던 1예 보고-

  • Kim, Hae-Ryoung (Department of Pathology, Yonsei University College of Medicine) ;
  • Kim, Hyun-Ki (Department of Pathology, Yonsei University College of Medicine) ;
  • Kim, Ho-Guen (Department of Pathology, Yonsei University College of Medicine) ;
  • Kim, Jin (Department of Oral Pathology, Yonsei University College of Dentistry) ;
  • Hong, Soon-Won (Department of Pathology, Yongdong Severance Hospital) ;
  • Kim, Se-Hoon (Department of Pathology, Yonsei University College of Medicine)
  • 김혜령 (연세대학교 의과대학 병리학교실) ;
  • 김현기 (연세대학교 의과대학 병리학교실) ;
  • 김호근 (연세대학교 의과대학 병리학교실) ;
  • 김진 (연세대학교 치과대학 구강병리학교실) ;
  • 홍순원 (영동세브란스병원 진단병리과) ;
  • 김세훈 (연세대학교 의과대학 병리학교실)
  • Published : 2006.03.31
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Abstract

Salivary duct carcinoma (SDC) is a rare primary salivary gland malignancy characterized by histological features similar to those of ductal carcinomas of the breast. It is regarded as a high-grade malignancy associated with frequent local recurrences and early distant metastases that require aggressive treatment. The typical fine needle aspiration cytology (FNAC) findings in SDC include cellular smears showing tumor cells with eccentric pleomorphic nuclei and a granular cytoplasm arranged in flat sheets or cribriform patterns against a necrotic background. However, the presence of mucin-containing cells in SDC has been rarely described. We report the FNAC findings in a patient with histologically confirmed SDC that demonstrated numerous mucin-containing cells and was subsequently misdiagnosed as a high-grade mucoepidermoid carcinoma. Here we discuss the problems involved in distinguishing SDC from high-grade mucoepidermoid carcinoma on the basis of cytologic findings alone.

Keywords

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