The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Cytologic Findings of Clear Cell Carcinoma of Ovary

난소의 원발 투명세포암종의 세포소견

  • Park, Ji-Young (Department of Pathology, Samsung Cheil Hospital, Sungkyunkwan University School of Medicine) ;
  • Kim, Hye-Sun (Department of Pathology, Samsung Cheil Hospital, Sungkyunkwan University School of Medicine) ;
  • Choi, Jong-Sun (Department of Pathology, Samsung Cheil Hospital, Sungkyunkwan University School of Medicine)
  • 박지영 (성균관대학교 삼성제일병원 병리과) ;
  • 김혜선 (성균관대학교 삼성제일병원 병리과) ;
  • 최종순 (성균관대학교 삼성제일병원 병리과)
  • Published : 2006.03.31
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Abstract

The objective of this study was to evaluate the cytomorphologic features of histologically confirmed clear cell carcinoma of the ovary and to evaluate the applicability of scrape or fine-needle aspiration cytology in making an intraoperative diagnosis. We reviewed scrape or fine-needle aspiration cytology findings in tissues taken from 6 patients with clear cell carcinoma of the ovary. The cytologic diagnosis was based primarily on findings in alcohol-fixed, hematoxylin-eosin (H-E) stained smears. The formation of material resembling a basement membrane was a characteristic finding in these smears. This extracellular hyaline material was stained light pink with H-E and was frequently found within tumor cell clusters as well as in the background material. Multinucleated giant cells were found occasionally. Each tumor cell had an abundant, clear, or granular cytoplasm with a distinct cellular membrane. Scrape cytology is a simple and rapid supportive method and could be helpful in diagnosing clear cell carcinoma of the ovary, especially when marked artifacts appear in the frozen section.

Keywords

References

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