Two cases of antibiotic therapy in dog infected with Brucella canis

Brucella canis 감염견에 대한 항균제 치료

  • 김성국 (경상북도 가축위생시험소) ;
  • 김영환 (경상북도 가축위생시험소) ;
  • 박인화 (경상북도 가축위생시험소) ;
  • 장성준 (경상북도 가축위생시험소) ;
  • 조광현 (경상북도 가축위생시험소) ;
  • 이양수 (경상북도 가축위생시험소)
  • Published : 2006.03.01

Abstract

For examination of antibiotic therapeutic efficacy in canine brucellosis, this examination was carried out two female bitches infected with Brucella canis in Gyeongbuk province, and used combicillin, baytril and doxycycline in susceptible antibiotics at B canis. During 18 month after the termination of antibiotic therapy, blood sample of the two bitches were examined for B canis antibody and antigen. The antibody of one bitch was disappeared at 5 month after antibiotic therapy and the other was continued at 18 month, but two bitches were not detected antigen by blood culture and PCR. Examination of blood chemical value (AST, ALT, urea, creatinine) of two bitches was increased in AST value during antibiotic therapy.

Keywords

References

  1. Timoney JF, Gillespie JH, Scott FW, et al. 1988. Hagan and Brunner's Microbiology and Infectious Disease of Domestic animals. 8th ed. Coms-tock Pub Ass Ithaca and London:148-152
  2. Beran GW. 1994. Handbook of Zoo-nosis. 2nd ed. CRC press, London:9-39
  3. Corbel MJ, Brinley-Morgan WJ. 1984. Genus Brucella Meyer and Shaw 1920, 173AL. In: Bergey's manual of systematic bacteriology, Vol 1. Krieg NR, Holt JG, Murray RGE, et al. Eds, Williams & Wilkins, Baltimore and London:377-388
  4. Carter GR, Chengappa MM, Roberts AW, et al. 1995. Essential of vete-rinary microbiology. 5th ed. Williams and Willkins, Baltimore : 199-204
  5. Carmichael LE, Bruner DW. 1968. Characteristics of a newly recognized species of brucella responsible for infectious canine abortion. Cornell Vet 48(4):579-592
  6. Shin S. and Carmichael LE. 1999. Canine brucellosis caused by Brucella canis. http://www.ivis.org/23. Nov
  7. Carmichael LE. 1970. Canine brucellosis ; The clinical disease, pathogenesis, and immune response, JAVMA 156(12):1726-1734
  8. Spink WW. 1970. Comments on canine brucellosis due to Brucella canis. JAVMA 156(12):1734-1736
  9. Morisset R. 1969. Epidemic canine brucellosis due to a new species, Brucella canis. Lancet 2(7628):1000-1002
  10. Moore JA. 1970, Epizootiology, diagnosis, and control of Brucella canis, JAVMA 156(12) : 1737-1740
  11. Pickerill PA. 1970. Comments on epizootiology and control of canine brucellosis. JAVMA 156(12):1741-1742
  12. Carmichael LE, Kenny M. 1968. Canine abortion caused by Brucella canis. JAVMA 152(6):605-616
  13. Jian H. 1992. Identification and characterization of 200 strains of Brucella canis under test from China. Wei sheng We Hsenh Pao 32:370-375
  14. Tak RB, Chun DK. 1972. Isolation of Brucella suis from aborted fetus of a dog. J Kor Soc Microbiol 7(1):17-20
  15. 박용호, 강승원, 주이석 등. 1984. 개 브루셀라 진단액 생산 기초시험 및 항체조사. 가축위생연구소 시험보고 94-98
  16. 문진산, 오기석, 박인철 등. 1999. 전남 지방의 소형견 번식장으로부터 발생한 canine brucellosis. 대한수의학회지 39(6):1099-1105
  17. 박청규, 오지연. 2001. 대구지역 개의 Brucella canis 감염에 대한 세균학적 및 혈청학적 조사, 대한수의학회지 41(1):67-71
  18. Chang CH, Lee JC, Lee CY, et al. 2000. Canine brucellosis in the Jindo. Korean J Vet Clin Med 17(2):321-326
  19. 김종완, 이영주. 2003. 집단 개사육농장에서의 canine brucellosis 발생 및 PCR-RFLP를 이용한 분리주의 특성조사. 대한수의학회지 43(1):67-75
  20. Wallach JC, Giambartolomei GH, et al. 2004. Human infection with M-strain of Brucella canis. http;//www.cdc.gov/eid. Emerg Infect Dis 10(1):146-148 https://doi.org/10.3201/eid1001.020622
  21. Nicoletti P. 1991. Further studies on the use of antibiotics in canine brucellosis. The Compendium 13 : 944-947
  22. 문진산, 오기석, 박인철 등. 1999. Brecella canis에 감염된 개의 항생제 치료 효과. 대한수의학회지 39(6) : 1106-1111
  23. Nicoletti P, Chase A. 1987. The use of antibiotics to control canine brucel-losis. The Compendium 9 : 1063-1066
  24. Flores-Castro R, Carmichael LE. 1981. Brucella canis infection in dogs treatment trials. Rev Latinoam Microbiol 23:75-79