Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
권호 표지

The minimum inhibitory concentration (MIC) of bee venom against bacteria isolated from pigs and chickens

돼지 및 닭에서 분리된 균에 대한 봉독의 최소억제농도(MIC)

  • Kim Soon-Tae (Northern Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Hwang Ji-Young (Northern Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Sung Myoung-Suk (Northern Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Je So-Yang (Northern Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Bae Dong-Rok (Northern Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Han Sang-Mi (National Institute of Agricultural Science & Technology) ;
  • Lee Sung-Hae (Northern Branch, Gyeongbuk Veterinary Service Laboratory)
  • 김순태 (경상북도 가축위생시험소 북부지소) ;
  • 황지영 (경상북도 가축위생시험소 북부지소) ;
  • 성명숙 (경상북도 가축위생시험소 북부지소) ;
  • 제소양 (경상북도 가축위생시험소 북부지소) ;
  • 배동록 (경상북도 가축위생시험소 북부지소) ;
  • 한상미 (농촌진흥청 농업과학기술원) ;
  • 이성해 (경상북도 가축위생시험소 북부지소)
  • Published : 2006.03.01
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Abstract

Bee venom is synthesized in the venom gland's of worker and queen bees and stored in their venom sacs. Bee venom is a rich source of enzymes, peptides and biogenic amines. there are at least 18 active components in the venom which have some pharmaceutical properties. This study was performed to evaluate minimum inhibitory concentration(MIC) of bee venom against bacteria isolated from pjgs and chickens with disease. In case of reference strains, the MIC $({\mu}g/m{\ell})$ of Staphylococcus aureus ATCC 6538, Streptococcus mutans ATCC 25175, and Salmonella typhimurium ATCC 6538 were 64, 64 and 32, respectively. In case of bacteria isolated from pig and chicken, the MIC of Staphylococcus aureus, Staphylococcus hyicus and Staphylococcus chromogenes were 8, 128 and 128, and that of 11 strains of Escherichia coli were 8 to >512 and that of 8 strains of Salmonella sup were >512. Antibacterial resistance test of 22 strains isolated from pig and chicken and 3 reference strains were performed by agar gel diffusion method, using 17 antibacterial drugs including penicillin, cefazolin, tetracycline and quinolone group. The multiple drug resistant patterns were found in most strains isolated from pig and chicken.

Keywords

References

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