참고문헌
- Benkert, O., Muller, M. and Szegedi, A. (2002). An overview of the clinical efficacy of mirtazapine. Hum. Psychopharmacol. 17, S23-S26 https://doi.org/10.1002/hup.397
- Bremner, J.D. (1995). A double-blind comparison of Org 3770, amitriptyline and placebo in major depression. J. Clin. Psychiatry. 56, 519-525
- De Boer, T., Nefkens, F. and van Helvoirt, A. (1994). The alpha 2-adrenoceptor antagonist Org 3770 enhances serotonin transmission in vivo. Eur. J. Pharmacol. 253, R5-6 https://doi.org/10.1016/0014-2999(94)90778-1
- Food and Drug Administration, Guidance for Industry: Bioanalytical method validation, Center for Drug Evaluation and Research, Rockville, MD, 200l
- Halakis, J.A. (1995). Org 3770 (mirtazapine) vs. trazodone: a placebo controlled trial in depressed elderly patients. Hum. Psychopharmacol. 10, S125-S133 https://doi.org/10.1002/hup.470100807
- Kamas, H.T., Shiu, G. and Shah, V.P. (1991). Validation of bioanalytical methods. Pharm. Res. 8, 421-426 https://doi.org/10.1023/A:1015882607690
- Marttila, M., Jaaskelainen, J., Jarvi, R. (1995). A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepine in patients with major depression. Eur. Neuropsychopharmacol. 5, 441-446 https://doi.org/10.1016/0924-977X(95)00016-I
- Maris, F.A., Dingler, E. and Niehues, S. (1999). High-performance liquid chromatographic saay with fluorescence detection for the routine monitoring of the antidepressant mirtazapine and its demthyl metabolite in human plasma. J. Chromatogr. B 721, 309-316
- Mullin, J., Lodge, A. and Bennie, E. (1996). A multicenter, double- blind, amitriptyline-controlled study of mirtazapine in patients with major depression. J. Psychopharmacol. 10, 235-240 https://doi.org/10.1177/026988119601000310
- Richou, H., Ruirny, P. and Charbaut, J. (1995). A multicenter, double- blind, clomipramine-controlled efficacy and safety study of Org 3770. Hum. Psychopharmacol. 10, 263-271 https://doi.org/10.1002/hup.470100403
- Smith, W.T., Glaudin, V., Panagides, J. and Gilvary, E. (1990). Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depressive disorder. Psychopharmacol. Bull. 26, 191- 196
- Paanakker, J.E. and Van Hal, H.J.M. (1987). Capillary gas chromatographic assay for the routine monitoring of the antidepressant mepirzepine in human plasma. J. Chromatogr. 417, 203-207 https://doi.org/10.1016/0378-4347(87)80109-3
- Timmer, C.J., Paanakker, J.E. and Vries, M.V. (1997). Mirtazapine phannacokinetics with two dosage regimens and two pharmaceutical formulations. Pharm. Res. 14,98-102 https://doi.org/10.1023/A:1012067703764
- Zivkov, M. and de Jongh, G. (1995). Org 3770 vs. amitriptyline: a 6-week randomized double-blind multicenter trial in hospitalized patients. Hum. Psychopharmacol. 10, 173-180 https://doi.org/10.1002/hup.470100302
- Zivkov, M., Roes, K.C.B. and Polis, A.G. (1995). Efficacy of Org 3770 (mirtazapine) vs. amitriptyline in patients with major depressive disorder: a meta-analysis. Hum. Psychopharmacol. 10, S135-S145 https://doi.org/10.1002/hup.470100808