Progress in Medical Physics (한국의학물리학회지:의학물리)
- Volume 17 Issue 1
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- Pages.24-31
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- 2006
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- 2508-4445(pISSN)
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- 2508-4453(eISSN)
Computer Assisted EPID Analysis of Breast Intrafractional and Interfractional Positioning Error
유방암 방사선치료에 있어 치료도중 및 분할치료 간 위치오차에 대한 전자포탈영상의 컴퓨터를 이용한 자동 분석
- Sohn Jason W. (Department on Radiation Oncology, Ireland Cancer Center, Case Western Reserve University School of Medicine, Cleveland) ;
- Mansur David B. (Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine) ;
- Monroe James I. (Department on Radiation Oncology, Ireland Cancer Center, Case Western Reserve University School of Medicine, Cleveland) ;
- Drzymala Robert E. (Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine) ;
- Jin Ho-Sang (Department of Radiation Oncology, University of Florida College of Medicine) ;
- Suh Tae-Suk (Department of Biomedical Engineering, Kangnam St. Mary's Hospital) ;
- Dempsey James F. (Department of Radiation Oncology, University of Florida College of Medicine) ;
- Klein Eric E. (Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine)
- Published : 2006.03.01
Abstract
Automated analysis software was developed to measure the magnitude of the intrafractional and interfractional errors during breast radiation treatments. Error analysis results are important for determining suitable planning target volumes (PTV) prior to Implementing breast-conserving 3-D conformal radiation treatment (CRT). The electrical portal imaging device (EPID) used for this study was a Portal Vision LC250 liquid-filled ionization detector (fast frame-averaging mode, 1.4 frames per second, 256X256 pixels). Twelve patients were imaged for a minimum of 7 treatment days. During each treatment day, an average of 8 to 9 images per field were acquired (dose rate of 400 MU/minute). We developed automated image analysis software to quantitatively analyze 2,931 images (encompassing 720 measurements). Standard deviations (
유방암 환자의 방사선치료에 있어 치료도중(intrafractional) 및 분할 치료 간(intefractional)에 발생되는 오차를 측정하는 자동분석소프트웨어를 개발하였다. 오차 분석 결과는 3차원 입체조형 방사선치료를 임상에 적용하기에 앞서 적절한 치료계획용적(Planning Target Volume, PTV)을 설정하는 데 있어 매우 중요하다. 본 연구에서는 전자포탈영상장치(Electrical Portal imaging Device, EPID)로써 Portal Vision LC250 액체 충전형 이온화 검출기를 사용하였다(fast frame-averaging 모드, 초당 1.4 프레임, 256X256 픽셀). 12명의 환자에 대해 최소 7일 이상씩 영상을 획득하였다. 매 치료마다 평균 8 내지 9개의 영상을 각 빔에 대해 얻었다(분당 400 MU 선량률). 총 2,931 (720 측정을 포함하는)개의 영상을 정량적으로 분석할 수 있는 자동화 영상 분석 소프트웨어를 개발하였다. 이를 통해 호흡으로 인해 발생하는 치료도중 오차와 분할 치료간 발생하는 분할치료오차의 표준편차(