대한한방부인과학회지 (The Journal of Korean Obstetrics and Gynecology)
- 제19권2호
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- Pages.162-185
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- 2006
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- 1229-4292(pISSN)
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- 2508-3619(eISSN)
가미귀출파징탕(加味歸朮破?湯)이 실험적으로 유발된 흰쥐의 자궁내막증에 미치는 영향
Effects of Gamigwichulpajing-Tang on the Development of Experimentally-induced Endometriosis in Rats
- 김여태 (세명대학교 한의과대학 부인과학교실) ;
- 이동녕 (세명대학교 한의과대학 부인과학교실) ;
- 서일복 (세명대학교 한의과대학 부인과학교실) ;
- 김형준 (세명대학교 한의과대학 부인과학교실)
- Kim, Yeo-Yae (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Lee, Dong-Nyung (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Seo, Il-Bock (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Kim, Hyung-Jun (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University)
- 발행 : 2006.05.31
초록
Purpose : This study was carried out to investigate the effects of Gamigwichulpajing-Tang(GGT) on the development of experimentally-induced endometriosis in rats. Materials and Methods : Endometriosis was induced in rats by auotransplanting uterine tissue to the peritoneum and devided them into three groups: (1) sham-operated group(n=8), (2) surgically induced endometriosis and untreated control group(n=8), (3)surgically induced endometriosis and GGT treated group. GGT(700mg/head) was orally administrated for 15days after operation. Then we measured the body weight, the volumes of endometriotic implants, the weight of uterus and ovary, and investigated the content of cytokines(MCP-1,